Global Patent Index - EP 1520035 A2

EP 1520035 A2 20050406 - METHOD FOR DETECTING THE VON WILLEBRAND FACTOR-CLEAVING PROTEASE ACTIVITY OF ADAMTS-13

Title (en)

METHOD FOR DETECTING THE VON WILLEBRAND FACTOR-CLEAVING PROTEASE ACTIVITY OF ADAMTS-13

Title (de)

VERFAHREN ZUM NACHWEIS DER VON WILLEBRAND-FAKTOR-SPALTENDEN PROTEASE-AKTIVITÄT VON ADAMTS-13

Title (fr)

PROCEDE DE DETECTION DE L'ACTIVITE DE LA PROTEASE DE CLIVAGE DU FACTEUR DE VON WILLEBRAND D'ADAMTS-13

Publication

EP 1520035 A2 20050406 (DE)

Application

EP 03762597 A 20030703

Priority

  • DE 10235348 A 20020703
  • EP 0307080 W 20030703

Abstract (en)

[origin: WO2004005451A2] The invention relates to a diagnostic method for determining the von Willebrand factor (VWF) cleaving activity of ADAMTS-13 in a test medium during which the test medium is mixed with 0.5 to 5 U/ml of a von Willebrand factor (VWF) that does not contain ADAMTS-13, and after incubation, the ADAMTS-13 activity is determined based on the drop in the VWF-mediated aggregation of thrombocytes.

IPC 1-7

C12Q 1/37

IPC 8 full level

C12Q 1/02 (2006.01); C12Q 1/37 (2006.01); G01N 33/86 (2006.01)

CPC (source: EP US)

C12Q 1/37 (2013.01 - EP US); G01N 33/86 (2013.01 - EP US)

Citation (search report)

See references of WO 2004005451A2

Citation (examination)

  • Presentation and Poster by the inventor Böhm et al. at the GTH Conference in February 2002
  • INTERNET CITATION: "BC von Willebrand Reagent", DADE BEHRING, 1 May 2001 (2001-05-01), pages 1 - 6, XP007902844, Retrieved from the Internet <URL:http://www.dadebehring.com/edbna2/ebusiness/home.jsp?lang=E> [retrieved on 20070829]

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

DE 20213920 U1 20030116; EP 1520035 A2 20050406; JP 2005535315 A 20051124; US 2005239153 A1 20051027; US 7291479 B2 20071106; WO 2004005451 A2 20040115; WO 2004005451 A3 20040429

DOCDB simple family (application)

DE 20213920 U 20020910; EP 0307080 W 20030703; EP 03762597 A 20030703; JP 2004518675 A 20030703; US 51982404 A 20041230