EP 1521779 A1 20050413 - COMPOUNDS THAT BIND TO THE INTERFERON-GAMMA, PREPARATION METHOD THEREOF AND MEDICAMENTS CONTAINING SAME
Title (en)
COMPOUNDS THAT BIND TO THE INTERFERON-GAMMA, PREPARATION METHOD THEREOF AND MEDICAMENTS CONTAINING SAME
Title (de)
INTERFERON-GAMMA BINDENDE VERBINDUNGEN, VERFAHREN ZU DEREN HERSTELLUNG, UND SIE ENTHALTENDE ARZNEIMITTEL
Title (fr)
COMPOSES SE LIANT A L INTERFERON-GAMMA, LEUR PROCEDE DE PREPARATION, ET MEDICAMENTS LES CONTENANT
Publication
Application
Priority
- FR 0301860 W 20030618
- FR 0207562 A 20020619
Abstract (en)
[origin: WO2004000887A1] The invention relates to a compound that can bind to the interferon-gamma (IFN<), which is selected from molecules having formula (I), in which X denotes a divalent spacer group having a sufficient length to enable each of the two oligosaccharide fragments A and B to bind to one of the peptide sequences 125 to 143 at the C-terminal ends of a homodimer of interferon-? (IFN-?) and n denotes an integer of between 0 and 10, e.g. equal to 0, 1, 2, 3, 4 or 5, and each R denotes independently a hydrogen atom, an SO3<- >group, or phosphate, on the condition that no SO3<- >group is located in position 3 of the glucosamine units of the compound (I). The invention also relates to the method of preparing the compounds, the complexes formed by the aforementioned compounds and the interferon-gamma and medicaments containing said compounds or complexes.
IPC 1-7
C08B 37/00; C08G 65/00; C08G 81/00; A61K 38/21; A61K 47/48; C08G 65/32
IPC 8 full level
A61K 38/21 (2006.01); A61K 31/726 (2006.01); A61K 31/727 (2006.01); A61K 47/48 (2006.01); A61P 1/04 (2006.01); A61P 19/02 (2006.01); A61P 25/00 (2006.01); A61P 29/00 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); A61P 31/12 (2006.01); A61P 33/00 (2006.01); A61P 35/00 (2006.01); A61P 37/04 (2006.01); A61P 37/06 (2006.01); C08B 37/00 (2006.01)
CPC (source: EP US)
A61K 31/727 (2013.01 - EP US); A61K 47/61 (2017.07 - EP US); A61P 1/04 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 31/12 (2017.12 - EP); A61P 33/00 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 37/04 (2017.12 - EP); A61P 37/06 (2017.12 - EP); C08B 37/00 (2013.01 - EP US); C08B 37/006 (2013.01 - EP US)
Citation (search report)
See references of WO 2004000887A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2841250 A1 20031226; FR 2841250 B1 20040723; AU 2003260601 A1 20040106; AU 2003260601 A8 20040106; CA 2489561 A1 20031231; EP 1521779 A1 20050413; JP 2005533881 A 20051110; US 2006166927 A1 20060727; WO 2004000887 A1 20031231
DOCDB simple family (application)
FR 0207562 A 20020619; AU 2003260601 A 20030618; CA 2489561 A 20030618; EP 03760740 A 20030618; FR 0301860 W 20030618; JP 2004514944 A 20030618; US 51817704 A 20041215