EP 1523315 A1 20050420 - 3-O-¬ALFA-L-RHAMNOPYRANOSYL-(1-2)-ALFA-L-RHAMNOPYRANOSYL-(1-4)-3BETA-D-GLUCOPYRANOSYL -25(S)-SPIROSTAN-3BETA-OL, PROCESS FOR ITS ISOLATION, AND ITS USE AS IMMUNOMODULATOR
Title (en)
3-O-¬ALFA-L-RHAMNOPYRANOSYL-(1-2)-ALFA-L-RHAMNOPYRANOSYL-(1-4)-3BETA-D-GLUCOPYRANOSYL -25(S)-SPIROSTAN-3BETA-OL, PROCESS FOR ITS ISOLATION, AND ITS USE AS IMMUNOMODULATOR
Title (de)
3-O-¬ALFA-L-RHAMNOPYRANOSYL-(1-2)-ALFA-L-RHAMNOPYRANOSYL-(1-4)-3BETA-D-GLUCOPYRANOSYL -25(S)-SPIROSTAN-3BETA-OL, PROZESS FÜR SEINE ISOLIERUNG UND SEINE VERWENDUNG ALS IMMUNOMODULATOR
Title (fr)
3-0-'ALFA-L-RHAMNOPYRANOSYL- (1-2) -ALPHA-L-RHAMNOPYRANOSYL- (1-4) -3BETA-D-GLUCOPYRANOSYL!-25 (S) -SPIROSTAN-3BETA-OL, SON PROCEDE D'ISOLEMENT ET SON UTILISATION EN TANT QU'IMMUNOMODULATEUR
Publication
Application
Priority
IN 0200057 W 20020321
Abstract (en)
[origin: WO03080067A1] The present invention provides a novel oligospirostanoside structurally constructed as 3-0[ alpha -L-rhamnopyranosyl-(1}2)- alpha -L-rhamnopyranosyl-(1}4)-0- beta -D-glucopyranosyl]-25(S)-spirostan-3 beta -ol isolated from Asparagus racemosus and biologically evaluated as a potent immunomodulatory agent and to a process of isolation of a novel oligospirostanoside from Asparagus racemosus. The present invention also relates to a pharmaceutical composition containing the novel oligospirostanoside and to a method for immunomodulation using said oligospirostanoside. The present invention also relates to the use of a novel oligospirostanoside 3-0-[ alpha -L-rhamnopyranosyl-(1}2)- alpha -L-rhamnopyranosyl-(1}4)-0- beta -D-glucopyranosyl]-25(S)-spirostan-3 beta -ol in immunomodulation in animals.
IPC 1-7
IPC 8 full level
A61P 37/02 (2006.01); C07J 71/00 (2006.01)
CPC (source: EP)
A61P 37/02 (2017.12); C07J 71/0005 (2013.01)
Citation (search report)
See references of WO 03080067A1
Citation (examination)
- US 6649745 B2 20031118 - HANDA SUKHDEV SWAMI [IN], et al
- DHULEY, J. N.: "Effect of some Indian herbs on Macrophage Functions in Ochratoxin A Treated Mice", J. ETHNOPHARMACOLOGY, vol. 58, 1997, pages 15 - 20, XP002196030
- Chemical Abstracts (online), database accession no. 2003:692769. & IN 177153 A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 03080067 A1 20031002; AU 2002242942 A1 20031008; EP 1523315 A1 20050420
DOCDB simple family (application)
IN 0200057 W 20020321; AU 2002242942 A 20020321; EP 02708616 A 20020321