EP 1523470 A1 20050420 - NOVEL COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS
Title (en)
NOVEL COMPOUNDS AS HISTONE DEACETYLASE INHIBITORS
Title (de)
NEUE VERBINDUNGEN ALS HISTONDEACETYLASEINHIBITOREN
Title (fr)
NOUVEAUX COMPOSES UTILISES COMME INHIBITEURS DE L'HISTONE-DEACETYLASE
Publication
Application
Priority
- DE 10233412 A 20020723
- EP 0307794 W 20030717
Abstract (en)
[origin: WO2004009536A1] The present invention is directed to compounds of the general formula (I) or pharmaceutical acceptable salts or physiologically functional derivatives thereof wherein: n is a non-aromatic ring system containing two to seven carbon atoms, wherein the ring system can contain one ore two double bonds; X is C, CH or CH2; Y is selected from C, CH, CH2, S, NR, CH2-CH2, H2C- -CH, HC- -CH2, C- -CH2, H2C- -C,or C - -C; one or more of the hydrogen atoms can opionally be substituted by one or more substituents R ; each of the dotted lines means a single, a double or triple bond with the exclusion of a combination of a triple with triple bond and a double with a triple bond; R is independently H, -CN, alkyl, cycloalkyl, aminoalkyl, alkylamino, alkoxy, -OH, -SH, alkylthio, hydroxyalkyl, hydroxyalkylamino, halogene, haloalkyl, haloalkyloxy; R is H, an alkyl or cycloalkyl group; Z is CH, C, or P; p is 0 or 1.
IPC 1-7
IPC 8 full level
A61P 1/16 (2006.01); A61K 31/16 (2006.01); A61P 3/10 (2006.01); A61P 7/06 (2006.01); A61P 29/00 (2006.01); A61P 31/04 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 43/00 (2006.01); C07C 259/06 (2006.01)
CPC (source: EP)
A61P 1/16 (2017.12); A61P 3/10 (2017.12); A61P 7/06 (2017.12); A61P 29/00 (2017.12); A61P 31/04 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 43/00 (2017.12); C07C 259/06 (2013.01); C07C 2601/08 (2017.04); C07C 2601/14 (2017.04)
Citation (search report)
See references of WO 2004009536A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004009536 A1 20040129; AU 2003254371 A1 20040209; CA 2491131 A1 20040129; CA 2491131 C 20130507; DE 10233412 A1 20040212; EP 1523470 A1 20050420; JP 2005533840 A 20051110; JP 4644829 B2 20110309
DOCDB simple family (application)
EP 0307794 W 20030717; AU 2003254371 A 20030717; CA 2491131 A 20030717; DE 10233412 A 20020723; EP 03765029 A 20030717; JP 2004522493 A 20030717