EP 1527169 A2 20050504 - LEECH EXTRACTS FOR STENTS
Title (en)
LEECH EXTRACTS FOR STENTS
Title (de)
EXTRAKTE AUS BLUTEGELN FÜR STENTS
Title (fr)
EXTRAITS DE SANGSUES POUR STENTS
Publication
Application
Priority
- FR 0302473 W 20030806
- FR 0210042 A 20020807
Abstract (en)
[origin: FR2843304A1] Stable complex (A) of destabilase (I), in monomeric form, able to aggregate into a polymeric complex to form a liposome. Stable complex (A) of destabilase (I), in monomeric form, able to aggregate into a polymeric complex to form a liposome. It is obtained from medicinal leeches by affinity chromatography on immobilized antibodies (Ab) directed against 6-ketoprostaglandins and elution of the (I) complex at high ionic strength. (A) is characterized by antithrombin activity of at least 700 ATU/mg; duration of recalcification of plasma at least 800 APC/mg; fibrinolytic activity at least 40 mm2/mg and by having immunomodulatory activity. An Independent claim is also included for implantable medical prostheses at least partly coated with a composition containing (A).
IPC 1-7
IPC 8 full level
A61K 8/66 (2006.01); A61K 8/72 (2006.01); A61K 31/5585 (2006.01); A61K 38/43 (2006.01); A61K 38/55 (2006.01); A61K 38/58 (2006.01); A61L 31/00 (2006.01); A61L 31/16 (2006.01); A61L 33/00 (2006.01); A61P 7/02 (2006.01); A61P 9/10 (2006.01); A61P 9/12 (2006.01); A61P 37/02 (2006.01); A61P 37/04 (2006.01); C07K 14/81 (2006.01); C07K 14/815 (2006.01); C12N 9/64 (2006.01)
CPC (source: EP US)
A61K 38/58 (2013.01 - EP US); A61L 31/005 (2013.01 - EP US); A61L 31/16 (2013.01 - EP US); A61P 7/02 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 37/02 (2017.12 - EP); A61P 37/04 (2017.12 - EP); C07K 14/8117 (2013.01 - EP US); C07K 14/815 (2013.01 - EP US); C12N 9/6402 (2013.01 - EP US); A61L 2300/254 (2013.01 - EP US); A61L 2300/30 (2013.01 - EP US); A61L 2300/42 (2013.01 - EP US); A61L 2300/426 (2013.01 - EP US); A61L 2300/626 (2013.01 - EP US)
Citation (search report)
See references of WO 2004015096A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2843304 A1 20040213; FR 2843304 B1 20051216; AU 2003282192 A1 20040225; EP 1527169 A2 20050504; JP 2005534331 A 20051117; US 2006110425 A1 20060525; WO 2004015096 A2 20040219; WO 2004015096 A3 20040408; WO 2004015096 A8 20050506
DOCDB simple family (application)
FR 0210042 A 20020807; AU 2003282192 A 20030806; EP 03756529 A 20030806; FR 0302473 W 20030806; JP 2004526981 A 20030806; US 52393705 A 20051116