EP 1529030 A2 20050511 - DERIVATIVES OF GLYCINERGIC R(+)-2-AMINO-3-HYDROXYPROPANOIC ACID
Title (en)
DERIVATIVES OF GLYCINERGIC R(+)-2-AMINO-3-HYDROXYPROPANOIC ACID
Title (de)
DERIVATE DER R(+)-2-AMINO-3-HYDROXYPROPIONSÄURE DIE DIE WIRKUNG VON GLYCIN BEEINFLUSSEN
Title (fr)
DERIVES DE L'ACIDE R(+)-2-AMINO-3-HYDROXYPROPANOIQUE A ACTION GLYCINERGIQUE
Publication
Application
Priority
- FR 0302447 W 20030801
- FR 0210306 A 20020814
Abstract (en)
[origin: US2005261372A1] The use of R(+)-2-amino-3-hydroxypropanoic acid derivatives, nitrogen substituted by a (C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, (C<SUB>3</SUB>-C<SUB>6</SUB>)alkenyl, 3-oxo(C<SUB>5</SUB>-C<SUB>6</SUB>)alkyl, 3-oxo(C<SUB>4</SUB>-C<SUB>6</SUB>)alken-2-yl, phenyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, phenyl(C<SUB>2</SUB>-C<SUB>6</SUB>)alkenyl, gem-diphenyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkyl, gem-diphenyl(C<SUB>2</SUB>-C<SUB>6</SUB>)alkenyl, (C<SUB>1</SUB>-C<SUB>6</SUB>)alcanoyl, optionally N-substituted alanyl, optionally N,N'-disubstituted lysinoyl, phenyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkylydene or gem-diphenyl(C<SUB>1</SUB>-C<SUB>6</SUB>)alkylidene group, and of the pharmaceutically acceptable salts thereof, for preparation of medicaments intended for the treatment of CNS diseases due to reduced glycinergic transmission, particularly for the treatment of autism, schizophrenia and Alzheimer's disease, is described.
IPC 1-7
C07C 229/22; A61K 31/198; C07C 237/12; C07C 271/22; C07C 251/24
IPC 8 full level
A61P 25/00 (2006.01); A61K 31/197 (2006.01); A61K 31/198 (2006.01); A61K 31/223 (2006.01); A61P 25/18 (2006.01); A61P 25/28 (2006.01); A61P 43/00 (2006.01); C07C 229/22 (2006.01); C07C 237/12 (2006.01); C07C 271/22 (2006.01)
CPC (source: EP KR US)
A61K 31/197 (2013.01 - EP KR US); A61K 31/198 (2013.01 - KR); A61P 25/00 (2017.12 - EP); A61P 25/18 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07C 229/22 (2013.01 - KR); C07C 2601/02 (2017.04 - EP US)
Citation (search report)
See references of WO 2004016580A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
US 2005261372 A1 20051124; US 7488755 B2 20090210; AU 2003274213 A1 20040303; AU 2003274213 B2 20080313; BR 0313740 A 20050719; CA 2497347 A1 20040226; CN 1675169 A 20050928; CR 7736 A 20081010; EA 010417 B1 20080829; EA 200500333 A1 20050825; EP 1529030 A2 20050511; FR 2843590 A1 20040220; FR 2843590 B1 20071005; GE P20074194 B 20070910; IL 166778 A0 20060115; JP 2005535715 A 20051124; KR 100756138 B1 20070905; KR 100890674 B1 20090326; KR 20050055697 A 20050613; KR 20070067250 A 20070627; MX PA05001761 A 20050425; NO 20050961 L 20050428; NZ 538633 A 20071026; PL 375413 A1 20051128; UA 80559 C2 20071010; WO 2004016580 A2 20040226; WO 2004016580 A3 20040408
DOCDB simple family (application)
US 52486905 A 20050211; AU 2003274213 A 20030801; BR 0313740 A 20030801; CA 2497347 A 20030801; CN 03818848 A 20030801; CR 7736 A 20050311; EA 200500333 A 20030801; EP 03758195 A 20030801; FR 0210306 A 20020814; FR 0302447 W 20030801; GE AU2003008683 A 20030801; IL 16677805 A 20050209; JP 2004528582 A 20030801; KR 20057002073 A 20050204; KR 20077013426 A 20070614; MX PA05001761 A 20030801; NO 20050961 A 20050223; NZ 53863303 A 20030801; PL 37541303 A 20030801; UA 2005001927 A 20030801