EP 1530593 A1 20050518 - HIGHLY BRANCHED, UNSUBSTITUTED OR LOW-SUBSTITUTED STARCH PRODUCTS, DIALYSIS SOLUTION AND PLASMA EXPANDER CONTAINING THE SAME, AND THE USE THEREOF
Title (en)
HIGHLY BRANCHED, UNSUBSTITUTED OR LOW-SUBSTITUTED STARCH PRODUCTS, DIALYSIS SOLUTION AND PLASMA EXPANDER CONTAINING THE SAME, AND THE USE THEREOF
Title (de)
HOCHVERZWEIGTE, NICHT ODER NIEDRIG SUBSTITUIERTE STÄRKEPRODUKTE, DIALYSELÖSUNG UND PLASMAEXPANDER ENTHALTEND DIESE UND DEREN VERWENDUNG
Title (fr)
PRODUITS D'AMIDON HAUTEMENT RAMIFIES, NON OU FAIBLEMENT SUBSTITUES, SOLUTION DE DIALYSE ET SUBSTITUT DU PLASMA CONTENANT LESDITS PRODUITS ET LEUR UTILISATION
Publication
Application
Priority
- DE 10237442 A 20020816
- EP 0308411 W 20030730
Abstract (en)
[origin: WO2004022602A1] Known hydroxyethylated or hydroxypropylated types of starch for use as a colloid osmotic agent in peritoneal dialysis or as a volume substitute (plasma expander) are disadvantageous in that a complete break-down by amylase is not possible by the more or less intense substitution by hydroxyethyl groups or hydroxypropyl groups. As a consequence, residual fragments remain behind in the organism that are eliminated only very slowly or are stored in diverse organs/tissues, particularly when administered in a high and/or long-term dose. According to the invention, these disadvantageous properties can be avoided to the greatest possible extent by using a highly branched, unsubstituted or low-substituted starch product, i.e. using a starch having a significantly higher degree of branching than amylopecin or having the alpha -1,6 degree of branching of glycogen or even exceeding this and, if substituted, having a degree of substitution MS of no greater than 0.3.
IPC 1-7
IPC 8 full level
A61K 31/718 (2006.01); A61M 1/28 (2006.01); A61P 7/08 (2006.01); C08B 30/20 (2006.01); C08B 31/12 (2006.01); C08B 31/18 (2006.01); C08B 35/04 (2006.01)
CPC (source: EP US)
A61M 1/287 (2013.01 - EP US); A61P 7/08 (2018.01 - EP); C08B 31/12 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
DE 10237442 A1 20040311; DE 10237442 B4 20040819; AU 2003251668 A1 20040329; CN 100340578 C 20071003; CN 1675248 A 20050928; EP 1530593 A1 20050518; HK 1080872 A1 20060504; JP 2005539107 A 20051222; JP 2010209349 A 20100924; JP 4594729 B2 20101208; US 2006032400 A1 20060216; US 7550446 B2 20090623; WO 2004022602 A1 20040318
DOCDB simple family (application)
DE 10237442 A 20020816; AU 2003251668 A 20030730; CN 03819356 A 20030730; EP 0308411 W 20030730; EP 03793660 A 20030730; HK 06100567 A 20060113; JP 2004533291 A 20030730; JP 2010117591 A 20100521; US 52442405 A 20050722