EP 1534336 A2 20050601 - ANTIBODIES THAT IMMUNOSPECIFICALLY BIND TO TRAIL RECEPTORS
Title (en)
ANTIBODIES THAT IMMUNOSPECIFICALLY BIND TO TRAIL RECEPTORS
Title (de)
ANTIKÖRPER, DIE IMMUNOSPEZIFISCH AN TRAIL-REZEPTOREN BINDEN
Title (fr)
ANTICORPS SE FIXANT DE FACON IMMUNOSPECIFIQUE A DES RECEPTEURS TRAIL
Publication
Application
Priority
- US 0325457 W 20030815
- US 40338202 P 20020815
- US 42573002 P 20021113
- US 46805003 P 20030506
Abstract (en)
[origin: WO2004016753A2] The present invention relates to antibodies and related molecules that immunospecifically bind to TRAIL receptor, TR4. Such antibodies have uses, for example, in the prevention and treatment of cancers and other proliferative disorders. The invention also relates to nucleic acid molecules encoding anti-TR4 antibodies, vectors and host cells containing these nucleic acids, and methods for producing the same. The present invention relates to methods and compositions for preventing, detecting, diagnosing, treating or ameliorating a disease or disorder, especially cancer and other hyperproliferative disorders, comprising administering to an animal, preferably a human, an effective amount of one or more antibodies or fragments or variants thereof, or related molecules, that immunospecifically bind to TRAIL receptor TR4.
IPC 1-7
IPC 8 full level
C07K 16/28 (2006.01)
CPC (source: EP)
A61K 39/39558 (2013.01); C07K 16/2878 (2013.01); A61K 2039/505 (2013.01); C07K 2317/622 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004016753 A2 20040226; WO 2004016753 A3 20040617; AU 2003259835 A1 20040303; AU 2003259835 A8 20040303; CA 2494372 A1 20040226; CA 2494372 C 20130528; EP 1534336 A2 20050601; EP 1534336 A4 20051214
DOCDB simple family (application)
US 0325457 W 20030815; AU 2003259835 A 20030815; CA 2494372 A 20030815; EP 03788476 A 20030815