Global Patent Index - EP 1535913 B1

EP 1535913 B1 20111102 - NOVEL QUATERNARY AMMONIUM COMPOUNDS

Title (en)

NOVEL QUATERNARY AMMONIUM COMPOUNDS

Title (de)

NEUE QUATERNÜRE AMMONIUMVERBINDUNGEN

Title (fr)

NOUVEAUX COMPOSES D'AMMONIUM QUATERNAIRE

Publication

EP 1535913 B1 20111102 (EN)

Application

EP 03791398 A 20030828

Priority

  • JP 0310980 W 20030828
  • JP 2002248586 A 20020828
  • JP 2002364725 A 20021217

Abstract (en)

[origin: EP1535913A1] Drugs useful for the treatment and prevention of hyperlipidemia, moreover drugs useful for the treatment and prevention of cholestasis-caused hepatopathy, particularly primary biliary cirrhosis and primary sclerosing cholangitis, and drugs for the treatment and prevention of obesity, fatty liver and steatohepatitis, containing as active ingredients benzothiazepine compounds having a thioamide bond and a quaternary ammonium substituent, represented by formula (1) below are provided. <CHEM> Also, drugs containing ileal bile acid transporter inhibiting compounds as active ingredients for the treatment and prevention of cholestasis-caused hepatopathy are provided.

IPC 8 full level

C07D 281/10 (2006.01); A61K 31/554 (2006.01); A61P 1/16 (2006.01); A61P 3/06 (2006.01); A61P 9/10 (2006.01); A61P 43/00 (2006.01); C07D 417/12 (2006.01)

CPC (source: EP KR)

A61P 1/16 (2017.12 - EP); A61P 3/04 (2017.12 - EP); A61P 3/06 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 281/10 (2013.01 - EP KR); C07D 417/12 (2013.01 - EP)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

EP 1535913 A1 20050601; EP 1535913 A4 20080409; EP 1535913 B1 20111102; AT E531701 T1 20111115; AU 2003257578 A1 20040319; AU 2003257578 B2 20090122; CA 2497345 A1 20040311; CA 2497345 C 20081014; CN 100494185 C 20090603; CN 1678597 A 20051005; JP 4497472 B2 20100707; JP WO2004020421 A1 20051215; KR 100990524 B1 20101029; KR 20050059088 A 20050617; WO 2004020421 A1 20040311

DOCDB simple family (application)

EP 03791398 A 20030828; AT 03791398 T 20030828; AU 2003257578 A 20030828; CA 2497345 A 20030828; CN 03820711 A 20030828; JP 0310980 W 20030828; JP 2004532766 A 20030828; KR 20057003204 A 20030828