EP 1537223 A2 20050608 - METHOD FOR THE PRODUCTION BY FERMENTATION OF SULPHUR-CONTAINING FINE CHEMICALS (METF)
Title (en)
METHOD FOR THE PRODUCTION BY FERMENTATION OF SULPHUR-CONTAINING FINE CHEMICALS (METF)
Title (de)
VERFAHREN ZUR FERMENTATIVEN HERSTELLUNG SCHWEFELHALTIGER FEINCHEMIKALIEN (METF)
Title (fr)
PROCEDE DE PRODUCTION PAR FERMENTATION DE PRODUITS CHIMIQUES FINS CONTENANT DU SOUFRE (METF)
Publication
Application
Priority
- DE 10239308 A 20020827
- EP 0309451 W 20030826
Abstract (en)
[origin: DE10239308A1] Fermentative production of at least one sulfur-containing fine chemical (I) by fermenting a (I)-producing coryneform bacterium (A), concentrating (I) in medium or cells, then isolating it. (A) expresses at least one heterologous nucleotide sequence (II) that encodes a protein (III) with methionine synthase (metF) activity. An Independent claim is also included for preparation of a feed additive (B) that contains L-methionine by culturing/fermenting an L-Met producing microorganisms, removing water from the fermentation broth and optionally also up to 100 % of the biomass, then drying the treated broth to recover (B) in powdered or granular form.
IPC 1-7
IPC 8 full level
A23K 1/00 (2006.01); A23K 1/16 (2006.01); C12N 15/09 (2006.01); C12P 13/04 (2006.01); C12P 13/12 (2006.01); C12R 1/15 (2006.01)
CPC (source: EP KR US)
C12P 11/00 (2013.01 - KR); C12P 13/04 (2013.01 - EP KR US); C12P 13/12 (2013.01 - EP KR US)
Citation (search report)
See references of WO 2004024931A2
Citation (examination)
BLANCO J. ET AL: "The folate branch of the methionine biosynthesis pathway in Streptomyces lividans: disruption of the 5,10-methylenetetrahydrofolate reductase gene leads to methionine auxotrophy", JOURNAL OF BACTERIOLOGY, vol. 180, no. 6, March 1998 (1998-03-01), pages 1586 - 1591, XP002191540
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
DE 10239308 A1 20040311; AU 2003258667 A1 20040430; BR 0313760 A 20050712; CN 100588714 C 20100210; CN 1688706 A 20051026; EP 1537223 A2 20050608; JP 2005537023 A 20051208; KR 20050034746 A 20050414; US 2006068476 A1 20060330; US 7282357 B2 20071016; WO 2004024931 A2 20040325; WO 2004024931 A3 20040422
DOCDB simple family (application)
DE 10239308 A 20020827; AU 2003258667 A 20030826; BR 0313760 A 20030826; CN 03820445 A 20030826; EP 0309451 W 20030826; EP 03794943 A 20030826; JP 2004535172 A 20030826; KR 20057003276 A 20050225; US 52590705 A 20050225