EP 1538208 A2 20050608 - Mutants of streptococcal toxin A and methods of use
Title (en)
Mutants of streptococcal toxin A and methods of use
Title (de)
Streptococcus Toxin A Mutanten und Verfahren zu deren Anwendung
Title (fr)
Mutants d'une toxine A de streptocoque et procédés d'utilisation
Publication
Application
Priority
- EP 96921589 A 19960607
- US 48026195 A 19950607
Abstract (en)
This invention is directed to mutant SPE-A toxins or fragments thereof, vaccine and pharmaceutical compositions, and methods of using the vaccine and pharmaceutical compositions. The preferred SPE-A toxin has at least one amino acid change and is substantially non-lethal compared with the wild type SPE-A toxin. The mutant SPE-A toxins can form vaccine compositions useful to protect animals against the biological activities of wild type SPE-A toxin.
IPC 1-7
IPC 8 full level
C12N 15/09 (2006.01); A61K 31/00 (2006.01); A61K 39/09 (2006.01); A61P 31/00 (2006.01); A61P 31/04 (2006.01); C07K 14/315 (2006.01); C12N 1/21 (2006.01); C12N 15/31 (2006.01); C12N 15/74 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP KR US)
A61K 39/09 (2013.01 - KR); A61P 31/00 (2018.01 - EP); A61P 31/04 (2018.01 - EP); C07K 14/315 (2013.01 - EP KR US); C12N 15/11 (2013.01 - KR); A61K 38/00 (2013.01 - EP US); A61K 39/00 (2013.01 - EP KR US)
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
EP 1538208 A2 20050608; EP 1538208 A3 20070523; AT E291625 T1 20050415; AU 6278296 A 19961230; AU 723116 B2 20000817; CA 2221480 A1 19961219; DE 69634510 D1 20050428; DE 69634510 T2 20060126; DK 0832241 T3 20050801; EP 0832241 A1 19980401; EP 0832241 B1 20050323; ES 2239332 T3 20050916; JP H11514844 A 19991221; KR 100456594 B1 20050617; KR 19990022750 A 19990325; PT 832241 E 20050831; US 2002054887 A1 20020509; US 2006039925 A1 20060223; US 6632441 B2 20031014; US 6870042 B1 20050322; WO 9640930 A1 19961219
DOCDB simple family (application)
EP 05075021 A 19960607; AT 96921589 T 19960607; AU 6278296 A 19960607; CA 2221480 A 19960607; DE 69634510 T 19960607; DK 96921589 T 19960607; EP 96921589 A 19960607; ES 96921589 T 19960607; JP 50226597 A 19960607; KR 19970709192 A 19971208; PT 96921589 T 19960607; US 62522103 A 20030722; US 8546605 A 20050321; US 9610252 W 19960607; US 97339198 A 19980312