EP 1539232 A1 20050615 - IMMUNIZATION AGAINST AUTOLOGOUS GHRELIN
Title (en)
IMMUNIZATION AGAINST AUTOLOGOUS GHRELIN
Title (de)
IMMUNISIERUNG GEGEN AUTOLOGES GHRELIN
Title (fr)
IMMUNISATION CONTRE LA GHRELINE AUTOLOGUE
Publication
Application
Priority
- DK 0300592 W 20030912
- DK PA200201345 A 20020912
- US 41016402 P 20020912
Abstract (en)
[origin: WO2004024183A1] Disclosed are novel methods that generally rely on immunization against autologous ghrelin. Immunization is preferably effected by administration of analogues of autologous ghrelin, said analogues being capable of inducing antibody production against the autologous ghrelin polypeptides. Especially preferred as an immunogen is autologous ghrelin, which has been modified by introduction of one single or a few foreign, immunodominant and promiscuous T-cell epitopes. Also disclosed are nucleic acid vaccination against ghrelin and vaccination using live vaccines as well as methods and means useful for the vaccination. Such methods and means include methods for the preparation of analogues and pharmaceutical formulations, as well as nucleic acid fragments, vectors, transformed cells, polypeptides and pharmaceutical formulations.
IPC 1-7
IPC 8 full level
A61K 39/00 (2006.01); A61P 3/04 (2006.01)
CPC (source: EP)
A61K 39/0005 (2013.01); A61P 3/04 (2017.12); A61P 3/06 (2017.12); A61P 43/00 (2017.12); C07K 14/54 (2013.01); C07K 14/555 (2013.01); C07K 14/575 (2013.01); C07K 2319/55 (2013.01); Y02A 50/30 (2017.12)
Citation (search report)
See references of WO 2004024183A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004024183 A1 20040325; WO 2004024183 B1 20040513; AU 2003263150 A1 20040430; CA 2498739 A1 20040325; EP 1539232 A1 20050615; JP 2006504413 A 20060209; MX PA05002699 A 20050920; NO 20051779 D0 20050411; NO 20051779 L 20050411
DOCDB simple family (application)
DK 0300592 W 20030912; AU 2003263150 A 20030912; CA 2498739 A 20030912; EP 03794825 A 20030912; JP 2004535024 A 20030912; MX PA05002699 A 20030912; NO 20051779 A 20050411