EP 1539788 A2 20050615 - METHODS AND COMPOSITIONS FOR USE IN SPLICEOSOME MEDIATED RNA i TRANS /i -SPLICING
Title (en)
METHODS AND COMPOSITIONS FOR USE IN SPLICEOSOME MEDIATED RNA i TRANS /i -SPLICING
Title (de)
VERFAHREN UND ZUSAMMENSETZUNGEN ZUR VERWENDUNG BEIM DURCH SPLEISSOSOMEN VERMITTELTEN RNA-TRANS-SPLEISSEN
Title (fr)
METHODES ET COMPOSITIONS DESTINEES A ETRE UTILISEES DANS LE I TRANS /I -EPISSAGE D'ARN INDUIT PAR UNE EPISSOSOME
Publication
Application
Priority
- US 0304622 W 20030212
- US 7502802 A 20020212
- US 7624802 A 20020212
Abstract (en)
[origin: WO03069311A2] The present invention provides methods and compositions for delivery of synthetic pre-trans-splicing molecules (synthetic PTMs) into a target cell. The compositions of the invention include synthetic pre-trans-splicing molecules (PTMs) with enhanced stability against chemical and enzymatic degradation. The synthetic PTMs are designed to interact with a natural target precursor messenger RNA molecule (target pre-mRNA) and mediate a trans-splicing reaction resulting in the generation of a novel chimeric RNA molecule (chimeric RNA).
IPC 1-7
IPC 8 full level
C12N 15/113 (2010.01); A61K 48/00 (2006.01)
CPC (source: EP)
A61P 11/00 (2017.12); A61P 17/06 (2017.12); C12N 15/113 (2013.01); A61K 48/00 (2013.01)
Citation (search report)
See references of WO 03069311A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
DOCDB simple family (publication)
WO 03069311 A2 20030821; WO 03069311 A3 20050421; AU 2003215249 A1 20030904; AU 2003215249 B2 20080703; CA 2475802 A1 20030821; EP 1539788 A2 20050615; JP 2006505242 A 20060216
DOCDB simple family (application)
US 0304622 W 20030212; AU 2003215249 A 20030212; CA 2475802 A 20030212; EP 03711065 A 20030212; JP 2003568382 A 20030212