Global Patent Index - EP 1546350 A1

EP 1546350 A1 20050629 - CELLS OVEREXPRESSING LIPOYL-PROTEIN LIGASE B-GENE FOR FERMENTATIVE PRODUCTION OF R-ALPHA-LIPONIC ACID

Title (en)

CELLS OVEREXPRESSING LIPOYL-PROTEIN LIGASE B-GENE FOR FERMENTATIVE PRODUCTION OF R-ALPHA-LIPONIC ACID

Title (de)

ZELLEN DIE, EIN LIPOYL-PROTEIN-LIGASE B-GEN ÖBEREXPRIMIEREN, ZUR FERMENTATIVEN HERSTELLUNG VON R-ALPHA-LIPONSÄURE

Title (fr)

CELLULES SUREXPRIMANT UN GENE DE LIGASE B DE PROTEINE LIPOYLE PERMETTANT DE PRODUIRE PAR FERMENTATION DE L'ACIDE LIPOIQUE R-ALPHA

Publication

EP 1546350 A1 20050629 (DE)

Application

EP 03810946 A 20030925

Priority

  • DE 10245993 A 20021002
  • EP 0310687 W 20030925

Abstract (en)

[origin: DE10245993A1] Cells (A) that secrete enantiomerically enriched R-alpha-lipoic acid (I) into the culture medium and over express the lipB (lipoyl-protein-ligase B) gene, are new. Independent claims are also included for: (1) a plasmid that contains a lipB gene under control of a promoter; (2) method for preparing (A) by introducing the plasmid of (1) into a starting cell; and (3) method for producing enantiomerically enriched (I) by culturing (A).

IPC 1-7

C12P 7/42; C12N 15/63; C12N 1/21; C07D 339/04

IPC 8 full level

C12N 1/21 (2006.01); C12N 9/00 (2006.01); C12N 15/63 (2006.01); C12P 11/00 (2006.01); C12P 17/00 (2006.01)

CPC (source: EP US)

C12N 9/93 (2013.01 - EP US); C12N 15/63 (2013.01 - EP US); C12P 11/00 (2013.01 - EP US); C12P 17/00 (2013.01 - EP US)

Citation (search report)

See references of WO 2004044211A1

Designated contracting state (EPC)

DE FR GB IT

DOCDB simple family (publication)

DE 10245993 A1 20040506; AU 2003301990 A1 20040603; EP 1546350 A1 20050629; TW 200416288 A 20040901; US 2006211098 A1 20060921; WO 2004044211 A1 20040527

DOCDB simple family (application)

DE 10245993 A 20021002; AU 2003301990 A 20030925; EP 0310687 W 20030925; EP 03810946 A 20030925; TW 92126913 A 20030929; US 52959005 A 20050329