EP 1546672 A1 20050629 - MICROFLUIDIC CHIP FOR BIOMOLECULE CRYSTALLIZATION
Title (en)
MICROFLUIDIC CHIP FOR BIOMOLECULE CRYSTALLIZATION
Title (de)
MIKROFLUIDISCHER CHIP ZUR BIOMOLEKüLKRISTALLISIERUNG
Title (fr)
PUCE MICROFLUIDIQUE UTILISEE DANS LA CRISTALLISATION DE BIOMOLECULES
Publication
Application
Priority
- US 0328513 W 20030909
- US 40948902 P 20020909
- US 41068502 P 20020913
- US 42762002 P 20021119
- US 32893102 A 20021223
- US 32901802 A 20021223
Abstract (en)
[origin: WO2004023106A1] A system for crystallizing a protein and other biomolecules, the general scheme of which is represented in Figure 1, comprises a flow channel (12) for conveying a solution containing the biomolecule to be crystallized and one or more substations (40, 50, 60, 70) related to the crystallization process formed along the flow channel. The system operates by flowing a biomolecule solution through the flow channel (12), then performing dialysis on a micro-scale to set crystallization conditions. After dialysis, the concentration of the biomolecule solution is changed by removing water or solvent from the biomolecule solution to promote formation of crystals in a segment of the flow channel. Formed crystals may be observed and harvested from the flow channel.
IPC 1-7
IPC 8 full level
G01N 1/00 (2006.01); G01N 33/68 (2006.01); B01D 61/24 (2006.01); B01D 61/28 (2006.01); B01D 63/08 (2006.01); B01L 3/00 (2006.01); C07K 1/14 (2006.01); C30B 7/00 (2006.01); C30B 29/58 (2006.01); G01N 1/18 (2006.01); G01N 37/00 (2006.01); B01L 3/06 (2006.01)
CPC (source: EP US)
B01D 61/243 (2013.01 - EP US); B01D 61/28 (2013.01 - EP); B01D 63/087 (2013.01 - EP); B01D 63/088 (2013.01 - EP); B01L 3/5027 (2013.01 - EP); C30B 7/00 (2013.01 - EP); C30B 29/58 (2013.01 - EP); B01L 3/06 (2013.01 - EP); B01L 2300/0681 (2013.01 - EP)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated extension state (EPC)
AL LT LV MK
DOCDB simple family (publication)
WO 2004023106 A1 20040318; AU 2003270552 A1 20040329; CA 2498332 A1 20040318; EP 1546672 A1 20050629; EP 1546672 A4 20080625; JP 2005538163 A 20051215
DOCDB simple family (application)
US 0328513 W 20030909; AU 2003270552 A 20030909; CA 2498332 A 20030909; EP 03752252 A 20030909; JP 2004534822 A 20030909