EP 1546714 A4 20071205 - COMPOSITIONS AND METHODS OF USE OF TARGETING PEPTIDES FOR DIAGNOSIS AND THERAPY OF HUMAN CANCER
Title (en)
COMPOSITIONS AND METHODS OF USE OF TARGETING PEPTIDES FOR DIAGNOSIS AND THERAPY OF HUMAN CANCER
Title (de)
ZUSAMMENSETZUNGEN UND VERFAHREN ZUR VERWENDUNG BEIM ABZIELEN AUF PEPTIDE ZUR DIAGNOSE UND THERAPIE VON KREBS IM MENSCHEN
Title (fr)
COMPOSITIONS ET PROCEDES D'UTILISATION DE PEPTIDES DE CIBLAGE CON US POUR LE DIAGNOSTIC ET LE TRAITEMENT DU CANCER HUMAIN
Publication
Application
Priority
- US 0234987 W 20021030
- US 0227836 W 20020830
Abstract (en)
[origin: WO2004020999A1] The present invention concerns compositions comprising and methods of identification and use of targeting peptides selective for cancer tissue, particularly prostate or ovarian cancer tissue. The method may comprise identifying endogenous mimeotopes of such peptides, such as GRP78, IL-11R alpha and hsp90. Antibodies against such targeting peptides or their mimeotopes may be used for detection, diagnosis and/or staging of prostate or ovarian cancer. In other embodiments, the compositions and methods concern novel type of gene therapy vector, known as adeno-associated phage (AAP). AAP are of use for targeted delivery of therapeutic agents to particular tissues, organs or cell types, such as prostate or ovarian cancer. In still other embodiments, targeting peptides selective for low-grade lipomas may be used for detection, diagnosis and targeted delivery of therapeutic agents.
IPC 1-7
IPC 8 full level
A61K 48/00 (2006.01); C07K 7/06 (2006.01); C07K 7/08 (2006.01); C12N 15/86 (2006.01); C12N 15/864 (2006.01); G01N 33/574 (2006.01)
CPC (source: EP)
A61K 48/00 (2013.01); C07K 7/06 (2013.01); C07K 7/08 (2013.01); C12N 15/86 (2013.01); G01N 33/57434 (2013.01); G01N 33/57449 (2013.01); C12N 2750/14143 (2013.01); C12N 2750/14145 (2013.01); C12N 2810/40 (2013.01); C12N 2810/405 (2013.01)
Citation (search report)
- [A] WO 0220822 A2 20020314 - UNIV TEXAS [US], et al
- [A] WO 0220724 A2 20020314 - UNIV TEXAS [US], et al
- [A] WO 0220723 A2 20020314 - UNIV TEXAS [US], et al
- [A] WO 0220722 A2 20020314 - UNIV TEXAS [US], et al
- [X] WO 0220769 A1 20020314 - UNIV TEXAS [US], et al
- See references of WO 2004020999A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
DOCDB simple family (publication)
WO 2004020999 A1 20040311; AU 2002364501 A1 20040319; CA 2496938 A1 20040311; EP 1546714 A1 20050629; EP 1546714 A4 20071205
DOCDB simple family (application)
US 0234987 W 20021030; AU 2002364501 A 20021030; CA 2496938 A 20021030; EP 02799873 A 20021030