EP 1551853 A1 20050713 - METHOD FOR THE SEPARATION OF TRIGLYCOALKALOIDS

Title (en)

METHOD FOR THE SEPARATION OF TRIGLYCOALKALOIDS

Title (de)

VERFAHREN ZUR AUFTRENNUNG VON TRIGLYCOALKALOIDEN

Title (fr)

PROCEDE DE SEPARATION DE TRIGLYCOALCALO DES

Publication

EP 1551853 A1 20050713 (EN)

Application

EP 03727026 A 20030613

Priority

AU 0300738 W 20030613
AU PS326302 A 20020628

Abstract (en)

[origin: WO2004002998A1] In accordance with the present invention there is provided a method for the separation of a triglycoalkaloid in which the triglycoside portion comprises alpha-L-rhamnopyranosyl-(1->2gal)-O-beta-D-glucopyranosyl-(1->3gal)-ß-D-galactopyranose (or 6-deoxy-a-L-mannopyranosyl-(1->2)-O-[ß-D-glucopyranosyl-(1->3)]-ß-D-galactopyranoside) ('an rhamnose-glucose-galactose triglycoalkaloid') from a triglycoalkaloid in which the triglycoside portion is a-L-rhamnopyranosyl-(1->2glu)-O-a-L-rhamnopyranosyl-(1->4glu)-ß-D-glucopyranose ('a rhamnose-rhamnose-glucose triglycoalkaloid') in a mixture containing both, the method comprising the steps of: Combining the mixture with a portion of alcoholic solvent; Causing or allowing a substantial portion of the rhamnose-rhamnose-glucose triglycoalkaloid to dissolve, thereby generating an alcoholic solution substantially of the rhamnose-rhamnose-glucose triglycoalkaloid , and a solid substantially comprising the rhamnose-glucose-galactose triglycoalkaloid; and Separating the solid substantially comprising the rhamnose-glucose-galactose triglycoalkaloid from the solution substantially of the rhamnose-rhamnose-glucose triglycoalkaloid.

IPC 1-7

C07H 17/00; C07H 17/02; C07H 1/08; A61K 31/706; A61P 35/00

IPC 8 full level

C07H 17/04 (2006.01); A61K 31/7048 (2006.01); A61K 31/706 (2006.01); A61P 35/00 (2006.01); C07H 1/08 (2006.01); C07H 17/00 (2006.01); C07H 17/02 (2006.01)

CPC (source: EP)

A61K 31/7048 (2013.01); A61K 31/706 (2013.01); A61P 35/00 (2017.12); C07H 1/08 (2013.01); C07H 17/00 (2013.01); C07H 17/02 (2013.01); C07H 17/04 (2013.01)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2004002998 A1 20040108; AU PS326302 A0 20020718; CA 2489682 A1 20040108; EP 1551853 A1 20050713; EP 1551853 A4 20070905; NZ 537268 A 20050826

DOCDB simple family (application)

AU 0300738 W 20030613; AU PS326302 A 20020628; CA 2489682 A 20030613; EP 03727026 A 20030613; NZ 53726803 A 20030613