EP 1554399 A1 20050720 - DETECTING THE RISK OF CARDIOVASCULAR DISEASES BY DETECTING MUTATIONS IN GENES, INCLUDING GENES ENCODING A2B-ADRENOCEPTOR AND APOLIPOPROTEIN B
Title (en)
DETECTING THE RISK OF CARDIOVASCULAR DISEASES BY DETECTING MUTATIONS IN GENES, INCLUDING GENES ENCODING A2B-ADRENOCEPTOR AND APOLIPOPROTEIN B
Title (de)
ERKENNUNG DES RISIKOS EINER HERZ-KREISLAUF-ERKRANKUNG MITTELS NACHWEIS VON GENMUTATIONEN, EINSCHLIESSLICH GENEN, DIE FUER A2B-ADRENOZEPTOREN UND APOLIPOPROTEIN B KODIEREN
Title (fr)
DETECTION DU RISQUE DE MALADIES CARDIO-VASCULAIRES PAR DETECTION DE MUTATIONS DANS DES GENES, Y COMPRIS DANS LES GENES CODANT POUR L'A2B-ADRENORECEPTEUR ET L'APOLIPOPROTEINE B
Publication
Application
Priority
- FI 0300740 W 20031007
- FI 20021783 A 20021007
Abstract (en)
[origin: WO2004031407A1] The present invention provides a method of identifying subject's susceptibility to cardiovascular diseases or risk of developing myocardial infarction (MI) or cerebrovascular stroke by detecting gene polymorphisms and other gene mutations from a biological sample of the subject and optionally obtaining information concerning the family and medical history, blood, serum, plasma and urinary analytes of the subject. Genetic variations or polymorphisms are detected in a number of genes, including genes encoding a2b-adrenoceptor and apolipoprotein B. The invention also provides a multivariate model, a combination or algorithm of variables which best describes the probability of cardiovascular diseases especially MI and stroke. The invention also relates to a test kit and software for accomplishing the method.
IPC 1-7
IPC 8 full level
C12Q 1/68 (2006.01); C12Q 1/6883 (2018.01)
IPC 8 main group level
C12Q (2006.01)
CPC (source: EP US)
C12Q 1/6883 (2013.01 - EP US); C12Q 2600/156 (2013.01 - EP US)
Citation (search report)
See references of WO 2004031407A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004031407 A1 20040415; AU 2003268976 A1 20040423; CA 2501481 A1 20040415; EP 1554399 A1 20050720; FI 115532 B 20050531; FI 20021783 A0 20021007; FI 20021783 A 20040408; US 2006166205 A1 20060727
DOCDB simple family (application)
FI 0300740 W 20031007; AU 2003268976 A 20031007; CA 2501481 A 20031007; EP 03750753 A 20031007; FI 20021783 A 20021007; US 53034703 A 20031007