EP 1556702 A2 20050727 - DIAGNOSTIC METHODS FOR TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES (PRION DISEASES)
Title (en)
DIAGNOSTIC METHODS FOR TRANSMISSIBLE SPONGIFORM ENCEPHALOPATHIES (PRION DISEASES)
Title (de)
METHODEN, UM ÜBERTRAGBARE SPONGIFORME ENZEPHALOPATHIEN (PRIONENERKRANKUNGEN), ZU DIAGNOSTIZIEREN
Title (fr)
METHODES DESTINEES A DIAGNOSTIQUER UNE ENCEPHALOPATHIE SPONGIFORME TRANSMISSIBLE
Publication
Application
Priority
- GB 0304574 W 20031023
- GB 0225245 A 20021030
- GB 0306290 A 20030319
Abstract (en)
[origin: WO2004040316A2] Transmissible spongiform encephalopathy (TSE) is diagnosed in a subject by using mass spectrometry to observe a polypeptide in a sample of body fluid taken from the subject. The polypeptide is differentially contained in the body fluid of TSE-infected subjects and non-infected subjects, and has a molecular weight in the range of from 1000 to 100000, but excluding the range of from 3500 to 30000. TSE can be diagnosed in a subject by determining a test amount of a polypeptide in a sample of body fluid, wherein the polypeptide is Cystatin C or a haemoglobin, a haemoglobin chain or a truncated chain or a fragment thereof which exhibits an immunological reaction to an antibody to bovine haemoglobin.
IPC 1-7
IPC 8 full level
G01N 33/68 (2006.01)
CPC (source: EP)
G01N 33/6896 (2013.01); G01N 2800/2828 (2013.01)
Citation (search report)
See references of WO 2004040316A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004040316 A2 20040513; WO 2004040316 A3 20041229; AU 2003274368 A1 20040525; AU 2003274368 B2 20081120; CA 2502198 A1 20040513; EP 1556702 A2 20050727; EP 2211181 A1 20100728; JP 2006504977 A 20060209; JP 4279836 B2 20090617
DOCDB simple family (application)
GB 0304574 W 20031023; AU 2003274368 A 20031023; CA 2502198 A 20031023; EP 03758352 A 20031023; EP 10160086 A 20031023; JP 2005501826 A 20031023