EP 1558590 A1 20050803 - ALPHA-PHENYL ACETANILIDE DERIVATIVES HAVING AN ACAT INHIBITING ACTIVITY AND THE THERAPEUTIC APPLICATION THEREOF
Title (en)
ALPHA-PHENYL ACETANILIDE DERIVATIVES HAVING AN ACAT INHIBITING ACTIVITY AND THE THERAPEUTIC APPLICATION THEREOF
Title (de)
ALPHA-PHENYL-ACETANILID-DERIVATE MIT ACAT-INHIBIERENDER WIRKUNG UND IHRE THERAPEUTISCHE VERWENDUNG
Title (fr)
DERIVES D'ALPHA-PHENYL ACETANILIDES PRESENTANT UNE ACTIVITE INHIBITRICE DE L'ACAT ET LEUR APPLICATION EN THERAPEUTIQUE
Publication
Application
Priority
- FR 0303038 W 20031015
- FR 0212855 A 20021016
Abstract (en)
[origin: WO2004035552A1] The invention relates to novel derivatives having general formula (I), wherein R1 represents an amino or hydroxyl group, R2 represents hydrogen or a methyl radical, R3 represents hydrogen or a fluorine atom and A represents: group a, formula (II), wherein n represents an integer from 5 to 11, inclusive, R4, R5, which can be identical or different, represent independently of one another hydrogen or a fluorine atom; group b, formula (III), wherein n, R4, R5 have the same meaning as above. The invention also relates to the pharmaceutical compositions containing at least one of the aforementioned compounds by way of an active principle and to the use of said derivatives for the production of medicaments which are intended for the treatment of hypercholesterolaemia or atherosclerosis.
IPC 1-7
C07D 257/04; C07C 317/28; A61K 31/167; A61K 31/41; A61P 9/10
IPC 8 full level
A61P 3/10 (2006.01); A61P 9/10 (2006.01); C07D 257/04 (2006.01)
CPC (source: EP US)
A61P 3/06 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/10 (2017.12 - EP); C07C 317/44 (2013.01 - EP US); C07D 257/04 (2013.01 - EP US)
Citation (search report)
See references of WO 2004035552A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004035552 A1 20040429; AU 2003288327 A1 20040504; BR 0315347 A 20050823; CA 2502505 A1 20040429; CN 1705648 A 20051207; EP 1558590 A1 20050803; FR 2845991 A1 20040423; FR 2845991 B1 20050204; JP 2006512302 A 20060413; MX PA05004064 A 20050608; US 2006135785 A1 20060622; ZA 200502694 B 20051110
DOCDB simple family (application)
FR 0303038 W 20031015; AU 2003288327 A 20031015; BR 0315347 A 20031015; CA 2502505 A 20031015; CN 200380101661 A 20031015; EP 03780228 A 20031015; FR 0212855 A 20021016; JP 2004544391 A 20031015; MX PA05004064 A 20031015; US 53123405 A 20051012; ZA 200502694 A 20050404