Global Patent Index - EP 1569684 A2

EP 1569684 A2 20050907 - USE OF HMGB FRAGMENTS AS ANTI-INFLAMMATORY AGENTS

Title (en)

USE OF HMGB FRAGMENTS AS ANTI-INFLAMMATORY AGENTS

Title (de)

VERWENDUNG VONHMGB-FRAGMENTEN ALS ENTZÜNDUNGSHEMMENDE MITTEL

Title (fr)

UTILISATION DE FRAGMENTS HMGB EN TANT QU'AGENTS ANTI-INFLAMMATOIRES

Publication

EP 1569684 A2 20050907 (EN)

Application

EP 03789973 A 20031120

Priority

  • US 0337507 W 20031120
  • US 42784102 P 20021120
  • US 42784602 P 20021120

Abstract (en)

[origin: WO2004046345A2] Compositions and methods are disclosed for inhibiting the release of a proinflammatory cytokine from a cell, and for inhibiting an inflammatory cytokine cascade in a patient. The compositions comprise an HMGB A box, and/or an antibody preparation that specifically binds to an HMGB B box, and/or an inhibitor of TNF biological activity. The methods comprise treating a cell or a patient with sufficient amounts of the composition to inhibit the release of the proinflammatory cytokine, or to inhibit the inflammatory cytokine cascade.

IPC 1-7

A61K 39/00; C07K 7/00; A61K 38/00

IPC 8 full level

A61K 38/17 (2006.01); C07K 14/47 (2006.01); A61K 38/00 (2006.01)

CPC (source: EP)

A61K 38/1709 (2013.01); A61P 1/04 (2017.12); A61P 1/18 (2017.12); A61P 3/04 (2017.12); A61P 9/00 (2017.12); A61P 9/02 (2017.12); A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 17/02 (2017.12); A61P 17/06 (2017.12); A61P 19/00 (2017.12); A61P 25/00 (2017.12); A61P 29/00 (2017.12); A61P 31/00 (2017.12); A61P 31/04 (2017.12); A61P 35/00 (2017.12); A61P 37/04 (2017.12); A61P 43/00 (2017.12); C07K 14/47 (2013.01)

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2004046345 A2 20040603; WO 2004046345 A3 20041202; AU 2003294488 A1 20040615; AU 2003294488 B2 20070524; CA 2506328 A1 20040603; EP 1569684 A2 20050907; EP 1569684 A4 20060802; JP 2006510619 A 20060330; NZ 540067 A 20070531

DOCDB simple family (application)

US 0337507 W 20031120; AU 2003294488 A 20031120; CA 2506328 A 20031120; EP 03789973 A 20031120; JP 2004554020 A 20031120; NZ 54006703 A 20031120