EP 1570059 A1 20050907 - METHOD FOR THE PRODUCTION OF R-ALPHA-LIPOIC ACID BY FERMENTATION
Title (en)
METHOD FOR THE PRODUCTION OF R-ALPHA-LIPOIC ACID BY FERMENTATION
Title (de)
VERFAHREN ZUR FERMENTATIVEN HERSTELLUNG VON R-ALPHA-LIPONSÄURE
Title (fr)
PROCEDE DE PRODUCTION D'ACIDE R-ALPHA-LIPOIQUE PAR FERMENTATION
Publication
Application
Priority
- DE 10258127 A 20021212
- EP 0313728 W 20031204
Abstract (en)
[origin: WO2004053131A1] The invention relates to a method for the production of R-alpha-lipoic acid by fermentation, characterised in that a cell with a weakened lipoyl protein ligase A activity is cultivated in a culture medium, whereby the cell precipitates enantiomerically pure R-alpha-lipoic acid in the free form in the culture medium and the enantiomerically pure R-alpha-lipoic acid is separated off from the culture medium.
IPC 1-7
IPC 8 full level
C12N 9/00 (2006.01); C12P 11/00 (2006.01); C12P 41/00 (2006.01)
CPC (source: EP US)
C12N 9/93 (2013.01 - EP US); C12P 11/00 (2013.01 - EP US); C12P 41/001 (2013.01 - EP US)
Citation (search report)
See references of WO 2004053131A1
Designated contracting state (EPC)
DE FR GB
DOCDB simple family (publication)
WO 2004053131 A1 20040624; AU 2003299300 A1 20040630; DE 10258127 A1 20040708; EP 1570059 A1 20050907; TW 200426218 A 20041201; US 2006234359 A1 20061019
DOCDB simple family (application)
EP 0313728 W 20031204; AU 2003299300 A 20031204; DE 10258127 A 20021212; EP 03799471 A 20031204; TW 92134778 A 20031210; US 53815705 A 20050608