Global Patent Index - EP 1570059 A1

EP 1570059 A1 20050907 - METHOD FOR THE PRODUCTION OF R-ALPHA-LIPOIC ACID BY FERMENTATION

Title (en)

METHOD FOR THE PRODUCTION OF R-ALPHA-LIPOIC ACID BY FERMENTATION

Title (de)

VERFAHREN ZUR FERMENTATIVEN HERSTELLUNG VON R-ALPHA-LIPONSÄURE

Title (fr)

PROCEDE DE PRODUCTION D'ACIDE R-ALPHA-LIPOIQUE PAR FERMENTATION

Publication

EP 1570059 A1 20050907 (DE)

Application

EP 03799471 A 20031204

Priority

  • DE 10258127 A 20021212
  • EP 0313728 W 20031204

Abstract (en)

[origin: WO2004053131A1] The invention relates to a method for the production of R-alpha-lipoic acid by fermentation, characterised in that a cell with a weakened lipoyl protein ligase A activity is cultivated in a culture medium, whereby the cell precipitates enantiomerically pure R-alpha-lipoic acid in the free form in the culture medium and the enantiomerically pure R-alpha-lipoic acid is separated off from the culture medium.

IPC 1-7

C12N 15/52; C12P 11/00

IPC 8 full level

C12N 9/00 (2006.01); C12P 11/00 (2006.01); C12P 41/00 (2006.01)

CPC (source: EP)

C12N 9/93 (2013.01); C12P 11/00 (2013.01); C12P 41/001 (2013.01)

Citation (search report)

See references of WO 2004053131A1

Designated contracting state (EPC)

DE FR GB

DOCDB simple family (publication)

WO 2004053131 A1 20040624; AU 2003299300 A1 20040630; DE 10258127 A1 20040708; EP 1570059 A1 20050907; TW 200426218 A 20041201; US 2006234359 A1 20061019

DOCDB simple family (application)

EP 0313728 W 20031204; AU 2003299300 A 20031204; DE 10258127 A 20021212; EP 03799471 A 20031204; TW 92134778 A 20031210; US 53815705 A 20050608