EP 1572067 A4 20090513 - CONJUGATES AND COMPOSITIONS FOR CELLULAR DELIVERY
Title (en)
CONJUGATES AND COMPOSITIONS FOR CELLULAR DELIVERY
Title (de)
KONJUGATE UND ZUSAMMENSETZUNGEN FÜR DIE ZELLULÄRE FREISETZUNG
Title (fr)
CONJUGUES ET COMPOSITIONS POUR ADMINISTRATION CELLULAIRE
Publication
Application
Priority
- US 0215876 W 20020517
- US 29221701 P 20010518
- US 30688301 P 20010720
- US 31186501 P 20010813
- US 36201602 P 20020306
Abstract (en)
[origin: WO02094185A2] This invention features conjugates, degradable linkers, compositions, methods of synthesis, and applications thereof, including folate, galactose, galactosamine, N-acetyl galactosamine, PEG, phospholipid, peptide and human serum albumin (HAS) derived conjugates of biologically active compounds, including antibodies, antivirals, chemotherapeutics, peptides, proteins, hormones nucleosides, nucleotides, non-nucleosides, and nucleic acids including enzymatic nucleic acids, DNAzymes, allozymes, antisense, dsRNA, siRNA, triplex oligonucleotides, 2,5-A chimeras, decoys and aptamers.
IPC 8 full level
A61K 47/48 (2006.01); G01N 33/53 (2006.01); A61K 6/00 (2006.01); A61K 9/14 (2006.01); A61K 31/519 (2006.01); A61K 31/52 (2006.01); A61K 31/7048 (2006.01); A61K 31/7052 (2006.01); A61K 31/706 (2006.01); A61K 31/7088 (2006.01); A61K 31/712 (2006.01); A61P 31/12 (2006.01); A61P 31/14 (2006.01); A61P 31/16 (2006.01); A61P 31/18 (2006.01); A61P 31/20 (2006.01); A61P 35/00 (2006.01); A61P 35/02 (2006.01); A61P 43/00 (2006.01); C07D 475/00 (2006.01); C07D 475/04 (2006.01); C07H 19/16 (2006.01); C07H 19/167 (2006.01); C07H 19/207 (2006.01); C07H 19/22 (2006.01); C07H 21/00 (2006.01); C07H 21/04 (2006.01); C08G 63/08 (2006.01); C12P 17/18 (2006.01); C12Q 1/68 (2006.01)
IPC 8 main group level
A61K (2006.01)
CPC (source: EP)
A61K 47/544 (2017.07); A61K 47/549 (2017.07); A61K 47/551 (2017.07); A61K 47/60 (2017.07); A61K 47/66 (2017.07); A61P 31/12 (2017.12); A61P 31/14 (2017.12); A61P 31/16 (2017.12); A61P 31/18 (2017.12); A61P 31/20 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 43/00 (2017.12); B82Y 5/00 (2013.01)
Citation (search report)
- [X] WO 9966063 A2 19991223 - ISIS PHARMACEUTICALS INC [US], et al
- [DA] WO 0044895 A1 20000803 - KREUTZER ROLAND [DE], et al
- [A] ELBASHIR SAYDA M ET AL: "RNA interference is mediated by 21- and 22-nucleotide RNAs", GENES AND DEVELOPMENT, COLD SPRING HARBOR LABORATORY PRESS, PLAINVIEW, NY, US, vol. 15, no. 2, 15 January 2001 (2001-01-15), pages 188 - 200, XP002204651, ISSN: 0890-9369
- See references of WO 02094185A2
Citation (examination)
THOMAS MINI ET AL: "Ligand-targeted delivery of small interfering RNAs to malignant cells and tissues.", ANNALS OF THE NEW YORK ACADEMY OF SCIENCES SEP 2009 LNKD- PUBMED:19796075, vol. 1175, September 2009 (2009-09-01), pages 32 - 39, ISSN: 1749-6632
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
DOCDB simple family (publication)
WO 02094185 A2 20021128; WO 02094185 A3 20070531; AU 2002316135 B2 20090108; AU 2002316135 B9 20090528; AU 2009200497 A1 20090226; CA 2447161 A1 20021128; EP 1572067 A2 20050914; EP 1572067 A4 20090513; EP 2415486 A2 20120208; EP 2415486 A3 20130109; EP 2415486 B1 20170222; EP 3231445 A1 20171018; HK 1244675 A1 20180817; JP 2005505504 A 20050224; JP 2009149652 A 20090709; JP 4358521 B2 20091104
DOCDB simple family (application)
US 0215876 W 20020517; AU 2002316135 A 20020520; AU 2009200497 A 20090210; CA 2447161 A 20020520; EP 02746413 A 20020517; EP 11184529 A 20020517; EP 17000268 A 20020517; HK 18103997 A 20180322; JP 2002590906 A 20020517; JP 2008332136 A 20081226