EP 1576098 A2 20050921 - A HUMAN CELL ASSAY TO DETERMINE EFFECT OF SAMPLE COMPOUNDS ON COL2 ENHANCER EXPRESSION
Title (en)
A HUMAN CELL ASSAY TO DETERMINE EFFECT OF SAMPLE COMPOUNDS ON COL2 ENHANCER EXPRESSION
Title (de)
ASSAY MIT MENSCHLICHEN ZELLEN ZUR BESTIMMUNG DER WIRKUNG VON PROBEVERBINDUNGEN AUF DIE EXPRESSION DES COL2-ENHANCERS
Title (fr)
DOSAGE DE CELLULE HUMAINE PERMETTANT DE DETERMINER L'EFFET DE COMPOSES D'ECHANTILLON SUR L'EXPRESSION DE L'AMPLIFICATEUR COL2
Publication
Application
Priority
- IB 0302256 W 20030526
- US 38615602 P 20020604
Abstract (en)
[origin: WO03102130A2] This invention relates to human chondrocyte activity (growth)/differentiation/production of extracellular matrix) and to the effect of Sox9transcription factor and Colt enhancer as a measure for such activity. It also relates to a chimeric cell and assay utilizing such cell useful in predicting the effect of sample compounds on chondrocyte activity as measured by Sox9 and Colt expression/activity.
IPC 1-7
IPC 8 full level
C12Q 1/00 (2006.01); C07K 14/47 (2006.01); C12N 5/00 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP)
C07K 14/4702 (2013.01); C12Q 1/6897 (2013.01)
Citation (search report)
See references of WO 03102130A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 03102130 A2 20031211; WO 03102130 A3 20060622; AU 2003233009 A1 20031219; AU 2003233009 A8 20031219; BR 0311594 A 20070427; CA 2488006 A1 20031211; EP 1576098 A2 20050921; JP 2006500915 A 20060112; MX PA04012042 A 20050307
DOCDB simple family (application)
IB 0302256 W 20030526; AU 2003233009 A 20030526; BR 0311594 A 20030526; CA 2488006 A 20030526; EP 03727809 A 20030526; JP 2004510372 A 20030526; MX PA04012042 A 20030526