EP 1576125 A2 20050921 - ACTIVATION OF HCV-SPECIFIC CELLS
Title (en)
ACTIVATION OF HCV-SPECIFIC CELLS
Title (de)
AKTIVIERUNG VON HCV-SPEZIFISCHEN ZELLEN
Title (fr)
ACTIVATION DE LYMPHOCYTES SPECIFIQUES DU VHC
Publication
Application
Priority
- US 0333610 W 20031024
- US 28134102 A 20021025
Abstract (en)
[origin: WO2004039950A2] The invention provides a method of activating hepatitis C virus (HCV)-specific T cells, including CD4<+> and CD8<+> T cells. HCV-specific T cells are activated using fusion proteins comprising HCV NS3, NS4, NS5a, and NS5b polypeptides, polynucleotides encoding such fusion proteins, or polypeptide or polynucleotide compositions containing the individual components of these fusions. The method can be used in model systems to develop HCV-specific immunogenic compositions, as well as to immunize a mammal against HCV.
IPC 1-7
IPC 8 full level
A61K 39/29 (2006.01); A61K 39/295 (2006.01); A61K 39/385 (2006.01); C07K 14/005 (2006.01); C07K 14/18 (2006.01)
CPC (source: EP)
A61P 31/14 (2017.12); C07K 14/005 (2013.01); A61K 2039/53 (2013.01); A61K 2039/57 (2013.01); C07K 2319/00 (2013.01); C12N 2770/24222 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004039950 A2 20040513; WO 2004039950 A3 20071122; AU 2003287188 A1 20040525; AU 2003287188 A8 20040525; CA 2505611 A1 20040513; EP 1576125 A2 20050921; EP 1576125 A4 20080903
DOCDB simple family (application)
US 0333610 W 20031024; AU 2003287188 A 20031024; CA 2505611 A 20031024; EP 03781368 A 20031024