EP 1578252 A2 20050928 - METHODS FOR EVALUATING GENETIC SUSCEPTIBILITY AND THERAPY FOR CHRONIC INFLAMMATORY DISEASES
Title (en)
METHODS FOR EVALUATING GENETIC SUSCEPTIBILITY AND THERAPY FOR CHRONIC INFLAMMATORY DISEASES
Title (de)
VERFAHREN ZUR AUSWERTUNG DER GENETISCHEN ANFÄLLIGKEIT UND THERAPIE FÜR CHRONISCHE ENTZÜNDUNGSKRANKHEITEN
Title (fr)
PROCEDES D'EVALUATION DE LA SUSCEPTIBILITE GENETIQUE ET TRAITEMENT DE MALADIES INFLAMMATOIRES CHRONIQUES
Publication
Application
Priority
- IL 0301115 W 20031230
- US 43665502 P 20021230
- US 47242303 P 20030522
Abstract (en)
[origin: WO2004058042A2] The invention discloses a knockout mouse that is homozygous for a RUNX3 null allele, as a novel model for chronic inflammatory disease. The present invention provides methods for treating T cell-related inflammatory conditions by cell therapy, gene therapy or antisense for up regulating or down regulating RUNX3. The invention further relates to methods of diagnosing and assessing predisposition to chronic inflammatory diseases. The present invention further provides methods for testing agents for effectiveness in treating and/or preventing diseases associated with chronic inflammatory or autoimmune conditions.
IPC 1-7
IPC 8 full level
A01K 67/00 (2006.01); A61B 1/00 (2006.01); A61K 31/7088 (2006.01); A61K 48/00 (2006.01); A61P 29/00 (2006.01); C07H 21/04 (2006.01); C12N 15/11 (2006.01); C12Q 1/00 (2006.01); C12Q 1/68 (2006.01); G01N 33/00 (2006.01); G01N 33/543 (2006.01)
IPC 8 main group level
A61B (2006.01)
CPC (source: EP US)
A61P 29/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C12Q 1/6883 (2013.01 - EP US); C12Q 2600/158 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004058042 A2 20040715; WO 2004058042 A3 20051208; AU 2003288524 A1 20040722; CA 2510362 A1 20040715; EP 1578252 A2 20050928; EP 1578252 A4 20091125; US 2006264393 A1 20061123; US 2009117046 A1 20090507
DOCDB simple family (application)
IL 0301115 W 20031230; AU 2003288524 A 20031230; CA 2510362 A 20031230; EP 03780599 A 20031230; US 35246009 A 20090112; US 54040203 A 20031230