Global Patent Index - EP 1578455 A4

EP 1578455 A4 20081231 - RADIOISOTOPE-ASSOCIATED POLYMERIC HYDROGEL MICROSPHERES AND METHODS FOR PRODUCING AND USING THE SAME

Title (en)

RADIOISOTOPE-ASSOCIATED POLYMERIC HYDROGEL MICROSPHERES AND METHODS FOR PRODUCING AND USING THE SAME

Title (de)

RADIOISOTOP-ASSOZIIERTE POLYMEREHYDROGEL-MIKROKÜGELCHEN UND VERFAHREN ZU IHRER HERSTELLUNG UND VERWENDUNG

Title (fr)

MICROSPHERES D'HYDROGELS POLYMERES ASSOCIEES A DES RADIOISOTOPES ET PROCEDES DE PRODUCTION ET D'UTILISATION DE CELLES-CI

Publication

EP 1578455 A4 20081231 (EN)

Application

EP 03779133 A 20031017

Priority

  • US 0333140 W 20031017
  • US 42354702 P 20021104

Abstract (en)

[origin: WO2004040972A2] The present invention relates to polymeric materials that are labeled with colloidal metals, preferably colloidal gold, to processes for producing the labeled polymeric material, and to methods of using the materials in prophylactic, therapeutic and cosmetic applications. Specifically, the invention relates to porous injectable and implantable microparticles, preferably microspheres, that are associated with radioactive colloidal metals such that the microparticles are visible or detectable under regular light, by radiological and/or magnetic resonance imaging techniques, or both. The microparticles having radioactive colloidal metals are particularly useful for embolization, radiation therapy, drug delivery, gene therapy, and other prophylactic or therapeutic medical applications.

IPC 1-7

A61K 51/12

IPC 8 full level

A61K 9/16 (2006.01); A61K 51/12 (2006.01)

CPC (source: EP)

A61K 9/1635 (2013.01); A61K 9/1658 (2013.01); A61K 51/1213 (2013.01); A61K 51/1255 (2013.01)

Citation (search report)

  • [X] US 6248057 B1 20010619 - MAVITY WILLIAM G [US], et al
  • [X] WO 0234300 A1 20020502 - SIRTEX MEDICAL LTD [AU], et al
  • [YD] WO 0023054 A1 20000427 - BIOSPHERE MEDICAL S A [FR]
  • [YD] US 5648100 A 19970715 - BOSCHETTI EGISTO [FR], et al
  • [XY] VAN ES R J ET AL: "Tumour embolization of the Vx2 rabbit head and neck cancer model with Dextran hydrogel and Holmium-poly(L-lactic acid) microspheres: a radionuclide and histological pilot study", JOURNAL OF CRANIO-MAXILLO-FACIAL SURGERY : OFFICIAL PUBLICATION OF THE EUROPEAN ASSOCIATION FOR CRANIO-MAXILLO-FACIAL SURGERY OCT 2001,, vol. 29, no. 5, 1 October 2001 (2001-10-01), pages 289 - 297, XP002500322
  • [X] SAKAKIBARA Y ET AL: "Prevascularization with gelatin micro spheres containing basic fibroblast growth factor enhances the benefits of cardiomyocyte transplantation", JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, MOSBY-YEAR BOOK, INC., ST. LOUIS, MO, US, vol. 124, no. 1, 1 July 2002 (2002-07-01), pages 50 - 56, XP002984640, ISSN: 0022-5223
  • [XY] DUCRET R P ET AL: "Therapeutic Embolization: Enhanced Radiolabeled Monitoring", RADIOLOGY, vol. 177, 1990, pages 571 - 575, XP002501359
  • [T] XP007906214, Retrieved from the Internet <URL:http://www.springer.com/chemistry/book/978-88-470-1103-8> [retrieved on 20081103]
  • See references of WO 2004040972A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2004040972 A2 20040521; WO 2004040972 A3 20041014; AU 2003285905 A1 20040607; CA 2507404 A1 20040521; EP 1578455 A2 20050928; EP 1578455 A4 20081231

DOCDB simple family (application)

US 0333140 W 20031017; AU 2003285905 A 20031017; CA 2507404 A 20031017; EP 03779133 A 20031017