EP 1578752 A1 20050928 - METHOD FOR PRODUCING PYRIDOXINE OR AN ACID ADDITION SALT THEREOF
Title (en)
METHOD FOR PRODUCING PYRIDOXINE OR AN ACID ADDITION SALT THEREOF
Title (de)
VERFAHREN ZUR HERSTELLUNG VON PYRIDOXIN ODER SEINES SÄUREADDITIONSSALZES
Title (fr)
PROCEDE DE PRODUCTION DE PYRIDOXINE OU DE SON SEL D'ADDITION D'ACIDE
Publication
Application
Priority
- DE 10261271 A 20021227
- EP 0314812 W 20031223
Abstract (en)
[origin: WO2004058774A1] The invention relates to a method for producing pyridoxine and the acid addition salts thereof, said method comprising the following steps: i. the Diels-Alder adduct (I) of 4-methyloxazole and a 4,7-dihydro-1,3-dioxepin is dissolved in a mixture of an organic solvent which can be at least partially mixed with water, and water, and the solution of (I) thus obtained is treated at an elevated temperature, optionally in the presence of a catalytically active quantity of an acid, until at least part of the compound (I) is converted into the corresponding 1,5-dihydro-8-methyl-[1,3]dioxepin-[5,6c]pyridin-9-ol (II); ii. the compound (II) of the solution obtained in step i., or the acid addition salt of said compound, is precipitated by adding a precipitant, and the compound (II) or the acid addition salt thereof is isolated; and iii. the compound (II) obtained in step i., or the acid addition salt thereof, is converted into pyridoxine or an acid addition salt thereof.
IPC 1-7
IPC 8 full level
C07D 213/67 (2006.01); C07D 498/08 (2006.01); C07D 498/18 (2006.01)
CPC (source: EP)
C07D 213/67 (2013.01)
Citation (search report)
See references of WO 2004058774A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004058774 A1 20040715; AU 2003300226 A1 20040722; CN 100351257 C 20071128; CN 1732175 A 20060208; DE 10261271 A1 20040708; EP 1578752 A1 20050928
DOCDB simple family (application)
EP 0314812 W 20031223; AU 2003300226 A 20031223; CN 200380107722 A 20031223; DE 10261271 A 20021227; EP 03799503 A 20031223