EP 1578951 A2 20050928 - DNA POLYMERASES WITH REDUCED BASE ANALOG DETECTION ACTIVITY
Title (en)
DNA POLYMERASES WITH REDUCED BASE ANALOG DETECTION ACTIVITY
Title (de)
DNA-POLYMERASE MIT REDUZIERTER NACHWEISAKTIVITÄTFÜR BASENANALOGE
Title (fr)
ADN POLYMERASES A ACTIVITE DE DETECTION ANALOGIQUE A BASE REDUITE
Publication
Application
Priority
- US 0333997 W 20031024
- US 28096202 A 20021025
- US 29868002 A 20021118
- US 40860103 A 20030407
Abstract (en)
[origin: WO2004038007A2] The invention relates to the generation and characterization of archaeal DNA polymerase mutants with reduced base analog detection activity. The invention further provides for archaeal DNA polymerase mutants with reduced base analog detection activity containing additional mutations that modulate other DNA polymerase activities including DNA polymerization or 3'-5' exonuclease activity. The invention also discloses methods and applications of DNA polymerases with reduced base analog detection activity.
IPC 1-7
IPC 8 full level
C07H 21/04 (2006.01); C12N 1/21 (2006.01); C12N 9/12 (2006.01); C12N 9/22 (2006.01); C12N 15/03 (2006.01); C12P 19/34 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP)
C07H 21/04 (2013.01); C12N 9/1252 (2013.01); C12Q 1/6869 (2013.01)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004038007 A2 20040506; WO 2004038007 A3 20050210; AU 2003301590 A1 20040513; CA 2503038 A1 20040506; EP 1578951 A2 20050928; EP 1578951 A4 20051116; JP 2006507012 A 20060302
DOCDB simple family (application)
US 0333997 W 20031024; AU 2003301590 A 20031024; CA 2503038 A 20031024; EP 03809647 A 20031024; JP 2005501697 A 20031024