EP 1579198 A1 20050928 - PHARMACEUTICAL COMPOSITIONS WITH IMPROVED DISSOLUTION
Title (en)
PHARMACEUTICAL COMPOSITIONS WITH IMPROVED DISSOLUTION
Title (de)
PHARMAZEUTISCHE ZUSAMMENSETZUNGEN MIT VERBESSERTER LÖSLICHKEIT
Title (fr)
COMPOSITIONS PHARMACEUTIQUES A DISSOLUTION AMELIOREE
Publication
Application
Priority
- US 0341273 W 20031224
- US 43751602 P 20021230
- US 44133503 P 20030121
- US 45121303 P 20030228
- US 45602703 P 20030318
- US 45660803 P 20030321
- US 45950103 P 20030401
- US 60109203 A 20030620
- US 0319574 W 20030620
- US 48671303 P 20030711
- US 48706403 P 20030711
- US 0327772 W 20030904
- US 66020203 A 20030911
- US 0328982 W 20030916
Abstract (en)
[origin: CA2511881A1] The invention relates to methods of screening mixtures containing a pharmaceutical compound and an excipient to identify properties of the pharmaceutical compound/excipient combination that retard solid-state nucleation. The invention further relates to increasing the solubility, dissolution and bioavailability of a drug with low solubility in gastric fluids conditions by combining the drug with a precipitation retardant and a n optional enhancer.
IPC 1-7
IPC 8 full level
A61K 31/415 (2006.01); C07B 63/00 (2006.01); G01N 21/27 (2006.01); G01N 25/08 (2006.01)
CPC (source: EP)
A61K 31/415 (2013.01); C07D 231/12 (2013.01)
Citation (search report)
See references of WO 2004061433A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
AU 2003303591 A1 20040729; CA 2511881 A1 20040722; CA 2511881 C 20130625; EP 1579198 A1 20050928; JP 2006517527 A 20060727; JP 5021934 B2 20120912
DOCDB simple family (application)
AU 2003303591 A 20031224; CA 2511881 A 20031224; EP 03808567 A 20031224; JP 2005508617 A 20031224