EP 1580278 A1 20050928 - PROCESS FOR PRODUCING MACROLIDE COMPOUND
Title (en)
PROCESS FOR PRODUCING MACROLIDE COMPOUND
Title (de)
VERFAHREN ZUR HERSTELLUNG EINERMAKROLIDVERBINDUNG
Title (fr)
PROCEDE DE PRODUCTION D'UN COMPOSE MACROLIDE
Publication
Application
Priority
- JP 0315170 W 20031127
- JP 2002346796 A 20021129
Abstract (en)
[origin: CA2507641A1] It is intended to provide a novel process for producing a 12-membered macrolide compound 11107D having an antitumor activity via biological conversion. The 12-membered macrolide compound 11107B represented by the formula (I), which is a starting substance, is incubated in the presence of a strain capable of converting it into the compound 11107D represented by the formula (II) and belonging to the genus Mortierella or Streptomyces or the family of Micromonosporaceae(for example, Streptomyces sp. AB-1704 strain (FERM BP-8551)) or a cultured cell preparation thereof together with oxygen and then the target compound 11107D is harvested from the incubation medium.
IPC 1-7
IPC 8 full level
C12P 17/16 (2006.01); A61K 31/336 (2006.01); A61P 35/00 (2006.01); C07D 407/06 (2006.01); C12N 1/20 (2006.01); C12R 1/645 (2006.01)
CPC (source: EP KR US)
A61K 31/336 (2013.01 - EP US); A61P 35/00 (2017.12 - EP); C07D 407/06 (2013.01 - EP KR US); C12P 17/16 (2013.01 - KR); C12P 17/162 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated extension state (EPC)
AL LT LV MK
DOCDB simple family (publication)
EP 1580278 A1 20050928; EP 1580278 A4 20100825; AU 2003284469 A1 20040623; AU 2003284469 B2 20080221; BR 0316746 A 20051018; CA 2507641 A1 20040617; CN 1717493 A 20060104; JP 4439401 B2 20100324; JP WO2004050890 A1 20060330; KR 20050086873 A 20050830; MX PA05005672 A 20050816; NO 20052568 D0 20050527; NO 20052568 L 20050629; NZ 540103 A 20070531; RU 2005120390 A 20060127; RU 2330069 C2 20080727; US 2006141589 A1 20060629; US 7745198 B2 20100629; WO 2004050890 A1 20040617
DOCDB simple family (application)
EP 03775924 A 20031127; AU 2003284469 A 20031127; BR 0316746 A 20031127; CA 2507641 A 20031127; CN 200380104432 A 20031127; JP 0315170 W 20031127; JP 2004556846 A 20031127; KR 20057009524 A 20050526; MX PA05005672 A 20031127; NO 20052568 A 20050527; NZ 54010303 A 20031127; RU 2005120390 A 20031127; US 53241205 A 20050422