Global Patent Index - EP 1581478 A1

EP 1581478 A1 20051005 - DHODH-INHIBITORS AND METHOD FOR THEIR IDENTIFICATION

Title (en)

DHODH-INHIBITORS AND METHOD FOR THEIR IDENTIFICATION

Title (de)

DHODH-INHIBITOREN UND VERFAHREN ZU DEREN IDENTIFIKATION

Title (fr)

INHIBITEURS DE L'ENZYME DHODH ET LEUR PROCEDE D'IDENTIFICATION

Publication

EP 1581478 A1 20051005 (EN)

Application

EP 03813575 A 20031217

Priority

  • EP 03813575 A 20031217
  • DE 10260799 A 20021223
  • DE 10260800 A 20021223
  • EP 0314435 W 20031217
  • EP 03028137 A 20031205

Abstract (en)

[origin: WO2004056747A1] The present invention relates to compounds of the general formula (I), or salts or isomeres thereof, wherein A is a 4-8 membered non-aromatic ring system, to compounds of the general formula (II), or salts or isomeres thereof, wherein A is a 3-8 membered non-aromatic ring system, wherein, when r = 0, there is no double bond between the carbon atoms carrying the substituents -CZ<1>- and -CZ<2>-;and to compounds of formula (III), wherein A is a heteroaromatic 5-membered ring system, which are capable of binding to the ubiquinone binding site of DHODH.

IPC 1-7

C07C 233/57; A61P 35/00; A61P 37/02; A61P 29/00; A61P 31/12; A61K 31/194; C07C 233/60; C07D 333/40; C07D 307/68; C07D 491/04; C07D 495/04; C07D 239/70; C07D 221/04; C07D 237/26

IPC 8 full level

A61K 31/194 (2006.01); A61P 29/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 37/02 (2006.01); C07C 233/57 (2006.01); C07C 233/60 (2006.01); C07C 235/40 (2006.01); C07C 235/82 (2006.01); C07D 221/04 (2006.01); C07D 237/26 (2006.01); C07D 239/70 (2006.01); C07D 307/68 (2006.01); C07D 333/38 (2006.01); C07D 333/40 (2006.01); C07D 491/04 (2006.01); C07D 495/04 (2006.01)

CPC (source: EP)

A61P 29/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 37/02 (2017.12); C07C 233/60 (2013.01); C07C 235/40 (2013.01); C07D 221/04 (2013.01); C07D 237/26 (2013.01); C07D 239/70 (2013.01); C07D 257/04 (2013.01); C07D 307/68 (2013.01); C07D 333/38 (2013.01); C07D 491/04 (2013.01); C07D 495/04 (2013.01); C07C 2601/08 (2017.04); C07C 2601/10 (2017.04)

Citation (search report)

See references of WO 2004056747A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

Designated extension state (EPC)

AL LT LV MK

DOCDB simple family (publication)

WO 2004056747 A1 20040708; AU 2003300530 A1 20040714; EP 1581478 A1 20051005

DOCDB simple family (application)

EP 0314435 W 20031217; AU 2003300530 A 20031217; EP 03813575 A 20031217