EP 1587803 A1 20051026 - PYRIMIDINE-4,6-DICARBOXYLIC ACID DIAMIDES FOR USE AS SELECTIVE MMP 13 INHIBITORS
Title (en)
PYRIMIDINE-4,6-DICARBOXYLIC ACID DIAMIDES FOR USE AS SELECTIVE MMP 13 INHIBITORS
Title (de)
PYRIMIDIN-4,6-DICARBONSÄUREDIAMIDE ALS SELEKTIVE MMP 13 INHIBITOREN
Title (fr)
DIAMIDES DE L'ACIDE PYRIMIDIN-4,6-DICARBOXYLIQUE UTILISES EN TANT QU'INHIBITEURS SELECTIFS DE MMP 13
Publication
Application
Priority
- EP 0314612 W 20031219
- DE 10300017 A 20030103
Abstract (en)
[origin: WO2004060883A1] The invention relates to the compounds of formula (I), wherein R1 to R7 are defined as in the claims, and to their use for selectively inhibiting collagenase (MMP 13). The pyrimidine-4,6-dicarboxylic acid diamides can therefore be used for treating degenerative articular diseases.
IPC 1-7
C07D 401/12; C07D 409/12; C07D 405/12; C07D 403/12; C07D 417/12; A61K 31/506; A61P 19/00; C07D 239/28
IPC 8 full level
A61P 19/00 (2006.01); C07D 239/28 (2006.01); C07D 401/12 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 417/12 (2006.01)
CPC (source: EP)
A61P 1/02 (2017.12); A61P 17/02 (2017.12); A61P 19/00 (2017.12); A61P 19/02 (2017.12); A61P 19/04 (2017.12); A61P 19/08 (2017.12); A61P 25/02 (2017.12); A61P 29/00 (2017.12); A61P 35/00 (2017.12); A61P 37/02 (2017.12); A61P 43/00 (2017.12); C07D 239/28 (2013.01); C07D 401/12 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 409/12 (2013.01); C07D 417/12 (2013.01)
Citation (search report)
See references of WO 2004060883A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004060883 A1 20040722; AR 042687 A1 20050629; AU 2003293951 A1 20040729; BR 0317834 A 20051129; CA 2512183 A1 20040722; DE 10300017 A1 20040715; EP 1587803 A1 20051026; JP 2006515595 A 20060601; MX PA05006401 A 20050819; PE 20040916 A1 20050125; TW 200505906 A 20050216
DOCDB simple family (application)
EP 0314612 W 20031219; AR P030104874 A 20031230; AU 2003293951 A 20031219; BR 0317834 A 20031219; CA 2512183 A 20031219; DE 10300017 A 20030103; EP 03789359 A 20031219; JP 2004564206 A 20031219; MX PA05006401 A 20031219; PE 2003001280 A 20031212; TW 92137550 A 20031231