EP 1592679 A2 20051109 - PROCESS FOR PREPARING SIMVASTATIN HAVING CONTROLLED RANGES OF SIMVASTATIN DIMER CONTENT
Title (en)
PROCESS FOR PREPARING SIMVASTATIN HAVING CONTROLLED RANGES OF SIMVASTATIN DIMER CONTENT
Title (de)
VERFAHREN ZUR HERSTELLUNG VON SIMVASTATIN UNTER KONTROLLE DES SIMVASTATIN-DIMER-GEHALTS
Title (fr)
PROCEDE DE PREPARATION DE SIMVASTATINE AYANT DES GAMMES REGULEES DE CONTENU DE DIMERE DE SIMVASTATINE
Publication
Application
Priority
- US 2004004304 W 20040211
- US 44676403 P 20030211
- US 46306503 P 20030415
Abstract (en)
[origin: WO2004071456A2] The present invention relates to a process for preparing simvastatin, wherein the simvastatin dimer content is controlled. More particularly, the present invention relates to a process for preparing simvastatin having a simvastatin dimer content of about 0.2 to about 0.4% wt. The present invention also relates to a process for preparing simvastatin having a simvastatin dimer content of less than about 0.2% wt. The present invention also discloses a commercial scale process of preparing simvastatin having a specified simvastatin dimer content which is reproducible.
IPC 1-7
IPC 8 full level
C07D 309/30 (2006.01)
CPC (source: EP KR US)
C07D 309/30 (2013.01 - EP KR US)
Citation (search report)
See references of WO 2004071456A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004071456 A2 20040826; WO 2004071456 A3 20041202; CA 2515179 A1 20040826; EP 1592679 A2 20051109; KR 20050098313 A 20051011; US 2004267044 A1 20041230; US 2006041148 A1 20060223; US 6995277 B2 20060207
DOCDB simple family (application)
US 2004004304 W 20040211; CA 2515179 A 20040211; EP 04710290 A 20040211; KR 20057014782 A 20050811; US 25530405 A 20051020; US 77753504 A 20040211