EP 1594535 A4 20060712 - IMMUNOGENIC ACUTE PHASE PROTEIN-ANTIGENIC MOLECULE COMPLEXES AND FUSION PROTEINS
Title (en)
IMMUNOGENIC ACUTE PHASE PROTEIN-ANTIGENIC MOLECULE COMPLEXES AND FUSION PROTEINS
Title (de)
IMMUNOGENE AKUTPHASEN-PROTEIN-ANTIGEN-MOLEKÜL-KOMPLEXE UND FUSIONSPROTEINE
Title (fr)
COMPLEXES DE MOLECULE ANTIGENE-PROTEINE DE PHASE AIGUE ET PROTEINES DE FUSION
Publication
Application
Priority
- US 2004003861 W 20040204
- US 44476803 P 20030204
Abstract (en)
[origin: WO2004069204A2] The present invention relates to complexes and fusion proteins comprising an acute phase protein and an antigenic molecule, for use in the treatment or prevention of a disease. The invention specifically provides for complexes comprising an acute phase protein noncovalently bound to, or alternatively crosslinked to, an antigenic molecule. The invention also specifically provides fusion proteins comprising an acute phase protein fused via a peptide bond to an antigenic molecule.
IPC 1-7
IPC 8 full level
A61K 39/00 (2006.01); A61K 39/385 (2006.01); A61K 47/48 (2006.01); C12N 15/62 (2006.01)
IPC 8 main group level
A61K (2006.01)
CPC (source: EP)
A61K 39/385 (2013.01); A61K 47/646 (2017.07); C12N 15/62 (2013.01); A61K 2039/6031 (2013.01); C07K 2319/40 (2013.01)
Citation (search report)
- [X] WO 0191787 A1 20011206 - UNIV CONNECTICUT HEALTH CT [US]
- [AD] SUZUE K ET AL: "HEAT SHOCK FUSION PROTEINS AS VEHICLES FOR ANTIGEN DELIVERY INTO THE MAJOR HISTOCOMPATIBILITY COMPLEX CLASS I PRESENTATION PATHWAY", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 94, November 1997 (1997-11-01), pages 13146 - 13151, XP002070395, ISSN: 0027-8424
- [A] BINDER R J ET AL: "Adjuvanticity of alpha 2-macroglobulin, an independent ligand for the heat shock protein receptor CD91", JOURNAL OF IMMUNOLOGY, THE WILLIAMS AND WILKINS CO. BALTIMORE, US, vol. 166, no. 8, April 2001 (2001-04-01), pages 4968 - 4972, XP002965476, ISSN: 0022-1767
- [A] BINDER R J ET AL: "Naturally formed or artificially reconstituted non-covalent alpha2-macroglobulin-peptide complexes elicit CD91-dependent cellular immunity", CANCER IMMUNITY, vol. 2, no. 16, 18 December 2002 (2002-12-18), pages 1 - 9,16, XP002965477, ISSN: 1424-9634
- [AD] QIN ZEN ET AL: "Binding site on human C-reactive protein (CRP) recognized by the leukocyte CRP-receptor", JOURNAL OF CELLULAR BIOCHEMISTRY, vol. 64, no. 1, 1997, pages 140 - 151, XP002369068, ISSN: 0730-2312
- See references of WO 2004069204A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004069204 A2 20040819; WO 2004069204 A3 20041125; AU 2004208848 A1 20040819; CA 2515107 A1 20040819; EP 1594535 A2 20051116; EP 1594535 A4 20060712
DOCDB simple family (application)
US 2004003861 W 20040204; AU 2004208848 A 20040204; CA 2515107 A 20040204; EP 04708276 A 20040204