EP 1596845 A1 20051123 - THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF
Title (en)
THERAPEUTIC USE OF ACYL GLYCEROLS AND THE NITROGEN- AND SULPHUR-CONTAINING ANALOGUES THEROF
Title (de)
THERAPEUTISCHE VERWENDUNG VON ACYLIERTEN GLYCEROLDERIVATEN UND DEREN STICKSTOFF- UND SCHWEFELANALOGEN
Title (fr)
UTILISATION THERAPEUTIQUE DE GLYCEROLS ACYLES ET DE LEURS ANALOGUES AZOTES ET SULFURES
Publication
Application
Priority
- FR 2004000322 W 20040212
- FR 0301691 A 20030212
Abstract (en)
[origin: FR2850870A1] The use of acylated glycerols, and their nitrogen and sulfur analogs (I), their optical and geometric isomers, racemates, salts, hydrates, and mixtures, for the prevention and treatment of neurodegenerative disorders. The use of acylated glycerols, and their nitrogen and sulfur analogs (I), their optical and geometric isomers, racemates, salts, hydrates, and mixtures, for the prevention and treatment of neurodegenerative disorders. [Image] G1O or N-R; G2, G3O, S, N-R4, with the proviso that G1, G2, and G3 may not simultaneously represent N-R or N-R4; R, R4H or optionally substituted, optionally unsaturated 1-5C alkyl; R1, R2, R3H, CO-R5, CO-(CH2)2n+1-X-R6, with the proviso that at least one is CO-(CH2)2n+1-X-R6; R5optionally substituted, optionally unsaturated, optionally cyclic alkyl having 1-25 C atoms in the main chain; R6optionally substituted, optionally unsaturated, optionally cyclic alkyl having 3-23 C atoms in the main chain and optionally containing one or more hetero groups selected from O, S, Se, SO and SO2; X : S, Se, SO, or SO2; n : 0-11. ACTIVITY : Antiparkinsonian; Nootropic; Neuroprotective. MECHANISM OF ACTION : Alpha Peroxisome Proliferator-Activated Receptor (PPARalpha ) Agonist.
IPC 1-7
A61K 31/045; A61K 31/22; A61K 31/25; A61K 31/265; A61P 25/28
IPC 8 full level
A61K 31/045 (2006.01); A61K 31/22 (2006.01); A61K 31/25 (2006.01); A61K 31/265 (2006.01); A61P 25/28 (2006.01)
CPC (source: EP US)
A61K 31/045 (2013.01 - EP US); A61K 31/22 (2013.01 - EP US); A61K 31/25 (2013.01 - EP US); A61K 31/265 (2013.01 - EP US); A61P 25/28 (2017.12 - EP)
Citation (search report)
See references of WO 2004073698A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated extension state (EPC)
AL LT LV MK
DOCDB simple family (publication)
FR 2850870 A1 20040813; FR 2850870 B1 20060728; EP 1596845 A1 20051123; US 2006154984 A1 20060713; WO 2004073698 A1 20040902
DOCDB simple family (application)
FR 0301691 A 20030212; EP 04710415 A 20040212; FR 2004000322 W 20040212; US 54251205 A 20050718