EP 1601782 A2 20051207 - DIAGNOSIS OF ALZHEIMER DISEASE BY THE DETERMINATION OF HUMAN PHOSPHODIESTERASE 8B (PDE8B)
Title (en)
DIAGNOSIS OF ALZHEIMER DISEASE BY THE DETERMINATION OF HUMAN PHOSPHODIESTERASE 8B (PDE8B)
Title (de)
DIAGNOSE VON ALZHEIMER DURCH DIE BESTIMMUNG VON HUMANEN PHOSPHODIESTERASE 8B (PDE8B)
Title (fr)
METHODE DIAGNOSTIQUE DE LA MALADIE D'ALZHEIMER PAR LA DETERMINATION DE LA PHOSPHODIESTERASE 8B HUMAINE (PDE8B)
Publication
Application
Priority
- EP 0311883 W 20031025
- EP 02024999 A 20021108
- EP 03772262 A 20031025
Abstract (en)
[origin: WO2004042077A2] The invention provides a human PDE8B which is associated with the disorders of the peripheral and central nervous system, cardiovascular diseases, endocrinological disease, urological disorders, reproduction disorders and metabolic disease. The invention also provides assays for the identification of compounds useful in the treatment or prevention of disorders of the peripheral and central nervous system, cardiovascular diseases, endocrinological disease, urological disorders, reproduction disorders and metabolic disease. The invention also features compounds which bind to and/or activate or inhibit the activity of PDE8B as well as pharmaceutical compositions comprising such compounds.
IPC 1-7
C12Q 1/44; C12Q 1/68; A61K 38/17; A61K 48/00; A61P 25/00; A61P 9/00; A61P 15/00; A61P 13/00; A61P 3/00
IPC 8 full level
A61K 38/17 (2006.01); A61K 38/46 (2006.01); A61K 48/00 (2006.01); A61P 3/00 (2006.01); A61P 9/00 (2006.01); A61P 13/00 (2006.01); A61P 15/00 (2006.01); A61P 25/00 (2006.01); C12N 9/16 (2006.01); C12Q 1/44 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP)
A61P 3/00 (2017.12); A61P 9/00 (2017.12); A61P 13/00 (2017.12); A61P 15/00 (2017.12); A61P 25/00 (2017.12); C12N 9/16 (2013.01); C12Q 1/44 (2013.01); C12Y 301/04053 (2013.01); A01K 2217/05 (2013.01); A61K 38/00 (2013.01); G01N 2333/916 (2013.01)
Citation (search report)
See references of WO 2004042077A2
Citation (examination)
SCHNEIDER M.: "A rational Approach to maximize success rate in target discovery.", ARCH. PHARM. PHARM. MED. CHEM., vol. 337, 2004, pages 625 - 633, XP002553686, DOI: doi:10.1002/ardp.200400913
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004042077 A2 20040521; WO 2004042077 A3 20050113; AU 2003279323 A1 20040607; EP 1601782 A2 20051207
DOCDB simple family (application)
EP 0311883 W 20031025; AU 2003279323 A 20031025; EP 03772262 A 20031025