Global Patent Index - EP 1603535 A4

EP 1603535 A4 20081015 - AROMATASE INHIBITOR DIAGNOSIS AND THERAPY

Title (en)

AROMATASE INHIBITOR DIAGNOSIS AND THERAPY

Title (de)

AROMATASE-HEMMER-DIAGNOSE UND THERAPIE

Title (fr)

DIAGNOSTIC ET TRAITEMENT FAISANT APPEL A UN INHIBITEUR DE L'AROMATASE

Publication

EP 1603535 A4 20081015 (EN)

Application

EP 04757537 A 20040317

Priority

  • US 2004008082 W 20040317
  • US 45551003 P 20030318

Abstract (en)

[origin: WO2004082626A2] The present invention provides pharmaceutical compositions which are useful for imaging and/or treating endometriosis. The compositions are useful for the treatment of reproductive age women, as well as post-menopausal women suffering from this disorder. The pharmaceutical composition is a liposome composition that includes a liposome carrier component that contains on its surface a moiety targeted for an endometriotic implant or leaky blood vessels within the implant. The inventive liposome composition includes an aromatase inhibitor and/or a radiolabeled complex encapsulated by the liposome component. A label capable of external detection can be included so as to permit the detection of an endometrial implant and/or diagnosis of the presence of endornetriosis in a patient. The label can be bound to the aromatase inhibitor. Alternatively, when the label is separate from the inhibitor, or when the inhibitor is not present, a radiolabeled complex can be included.

IPC 8 full level

A61K 9/127 (2006.01); A61K 9/133 (2006.01); A61K 51/12 (2006.01); A61P 15/00 (2006.01)

IPC 8 main group level

A61K (2006.01)

CPC (source: EP)

A61K 9/1271 (2013.01); A61K 9/1272 (2013.01); A61K 51/1234 (2013.01); A61P 15/00 (2017.12)

Citation (search report)

Designated contracting state (EPC)

DE ES FR GB IT

DOCDB simple family (publication)

WO 2004082626 A2 20040930; WO 2004082626 A3 20041111; EP 1603535 A2 20051214; EP 1603535 A4 20081015

DOCDB simple family (application)

US 2004008082 W 20040317; EP 04757537 A 20040317