EP 1608632 B1 20091230 - QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS
Title (en)
QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS
Title (de)
CHINAZOLIN-VERBINDUNGEN ALS IONENKANAL MODULATOREN
Title (fr)
QUINAZOLINES UTILISEES COMME MODULATEURS DE CANAUX IONIQUES
Publication
Application
Priority
- US 2004006451 W 20040303
- US 45145803 P 20030303
- US 46379703 P 20030418
Abstract (en)
[origin: WO2004078733A1] The present invention relates to quinazoline compounds of formula (I) useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders. or a pharmaceutically acceptable derivative thereof, wherein R<1>, X, R<3>, x, and ring A are as defined in the present application.
IPC 8 full level
C07D 239/94 (2006.01); A61K 31/517 (2006.01); A61K 31/5377 (2006.01); A61K 31/541 (2006.01); C07D 239/91 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 403/14 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/04 (2006.01); C07D 409/12 (2006.01); C07D 409/14 (2006.01); C07D 413/02 (2006.01); C07D 413/12 (2006.01); C07D 417/02 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); C07D 498/04 (2006.01)
IPC 8 main group level
C07D (2006.01)
CPC (source: EP KR US)
A61K 31/517 (2013.01 - KR); A61P 1/04 (2017.12 - EP); A61P 7/12 (2017.12 - EP); A61P 9/06 (2017.12 - EP); A61P 19/00 (2017.12 - EP); A61P 19/02 (2017.12 - EP); A61P 21/02 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/04 (2017.12 - EP); A61P 25/06 (2017.12 - EP); A61P 25/08 (2017.12 - EP); A61P 25/14 (2017.12 - EP); A61P 25/22 (2017.12 - EP); A61P 25/24 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 29/02 (2017.12 - EP); A61P 35/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 239/91 (2013.01 - EP US); C07D 239/94 (2013.01 - EP KR US); C07D 401/04 (2013.01 - EP KR US); C07D 401/12 (2013.01 - EP KR US); C07D 401/14 (2013.01 - EP KR US); C07D 403/12 (2013.01 - EP KR US); C07D 403/14 (2013.01 - EP US); C07D 405/12 (2013.01 - EP KR US); C07D 405/14 (2013.01 - EP KR US); C07D 409/04 (2013.01 - EP KR US); C07D 409/12 (2013.01 - EP KR US); C07D 413/12 (2013.01 - EP KR US); C07D 417/12 (2013.01 - EP US); C07D 471/04 (2013.01 - EP US); C07D 487/04 (2013.01 - EP US)
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL LT LV MK
DOCDB simple family (publication)
WO 2004078733 A1 20040916; AR 044502 A1 20050914; AT E453629 T1 20100115; AU 2004217891 A1 20040916; AU 2004217891 B2 20110623; BR PI0408026 A 20060207; CA 2517844 A1 20040916; CL 2004000409 A1 20050107; DE 602004024873 D1 20100211; EP 1608632 A1 20051228; EP 1608632 B1 20091230; ES 2338553 T3 20100510; HK 1088314 A1 20061103; IL 170636 A 20120830; JP 2006522119 A 20060928; JP 5247027 B2 20130724; KR 20050108379 A 20051116; NO 20054546 D0 20051003; NO 20054546 L 20051125; NZ 542664 A 20090331; PE 20041059 A1 20050207; RU 2005130486 A 20060510; RU 2378260 C2 20100110; TW 200426147 A 20041201; US 2004248890 A1 20041209; US 2011021495 A1 20110127; US 7678802 B2 20100316; US 8343980 B2 20130101; UY 28215 A1 20040930
DOCDB simple family (application)
US 2004006451 W 20040303; AR P040100670 A 20040303; AT 04716887 T 20040303; AU 2004217891 A 20040303; BR PI0408026 A 20040303; CA 2517844 A 20040303; CL 2004000409 A 20040302; DE 602004024873 T 20040303; EP 04716887 A 20040303; ES 04716887 T 20040303; HK 06108587 A 20060802; IL 17063605 A 20050904; JP 2006509028 A 20040303; KR 20057016287 A 20050901; NO 20054546 A 20051003; NZ 54266404 A 20040303; PE 2004000236 A 20040303; RU 2005130486 A 20040303; TW 93105557 A 20040303; US 68816310 A 20100115; US 79268804 A 20040303; UY 28215 A 20040303