EP 1611127 A2 20060104 - 4-SUBSTITUED QUINOLEIN DERIVATIVES WITH ANTIMICROBIAL ACTIVITY
Title (en)
4-SUBSTITUED QUINOLEIN DERIVATIVES WITH ANTIMICROBIAL ACTIVITY
Title (de)
4-SUBSTITUIERTE CHINOLEIN DERIVATE MIT ANTIMIKROBIELLER WIRKUNG
Title (fr)
DERIVES DE QUINOLEINES-4-SUBSTITUEES AVEC UNE ACTIVITE ANTIMICROBIENNE
Publication
Application
Priority
- FR 2004000783 W 20040329
- FR 0303812 A 20030328
Abstract (en)
[origin: CA2520764A1] The invention concerns 4-substituted quinoline derivatives active as antimicrobial agents, of general formula (I), wherein: X1, X2, X3, X4 and X5 respectively represent >C-R'1 to >C-R'5, or not more than one represen ts N; Y represents CHR, CO, CROH, CRNH2, CRF or CF2, R being hydrogen or alkyl; m is 1, 2, or 3 and n is 0, 1 or 2; Z is CH2 or Z represents O, S, SO, SO2 and, i n that case, n is equal to 2; R2 represents -CO2R, -CH2CO2R, -CH2-CH2CO2R, - CH2OH or -CH2-CH2OH, R being as defined above; R3 represents phenyl, heteroaryl or alk-R~3, wherein alk is an alkyl and R~3 represents various groups, optionally oxygenated, sulphured or aminated, in their enantiomeric or diastereoisomeric forms or mixtures thereof, and optionally in their syn or anti forms or mixtures thereof, as well as their salts.
IPC 1-7
IPC 8 full level
A61P 31/04 (2006.01); C07D 401/06 (2006.01); C07D 409/14 (2006.01); C07D 413/06 (2006.01)
CPC (source: EP KR)
A61P 31/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); C07D 401/06 (2013.01 - EP KR); C07D 409/14 (2013.01 - EP KR); C07D 413/06 (2013.01 - EP KR)
Citation (search report)
See references of WO 2004087647A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
FR 2852954 A1 20041001; FR 2852954 B1 20060714; AR 043941 A1 20050817; AU 2004226207 A1 20041014; CA 2520764 A1 20041014; CN 1795191 A 20060628; EA 010403 B1 20080829; EA 200501526 A1 20060428; EP 1611127 A2 20060104; HR P20050855 A2 20051231; JP 2006522779 A 20061005; KR 20050115321 A 20051207; RS 20050806 A 20071231; TW 200505899 A 20050216; WO 2004087647 A2 20041014; WO 2004087647 A3 20050127
DOCDB simple family (application)
FR 0303812 A 20030328; AR P040101023 A 20040326; AU 2004226207 A 20040329; CA 2520764 A 20040329; CN 200480014510 A 20040329; EA 200501526 A 20040329; EP 04742385 A 20040329; FR 2004000783 W 20040329; HR P20050855 A 20050927; JP 2006505763 A 20040329; KR 20057018388 A 20050928; TW 93107677 A 20040322; YU P20050806 A 20040329