Global Patent Index - EP 1611151 A4

EP 1611151 A4 20070822 - STQ-PEPTIDES

Title (en)

STQ-PEPTIDES

Title (de)

STQ-PEPTIDE

Title (fr)

PEPTIDES STQ

Publication

EP 1611151 A4 20070822 (EN)

Application

EP 04758409 A 20040326

Priority

  • US 2004009332 W 20040326
  • US 45852303 P 20030328

Abstract (en)

[origin: US2009226369A1] The invention describes methods for inhibiting angiogenesis in a tissue by administering an antagonist that specifically binds to a proteolyzed or denatured laminin with substantially greater affinity than to the native form of laminin. Methods utilizing such antagonists for therapeutic treatment of tumor growth, tumor metastasis or of restenosis also are described, as are methods to use such antagonists as diagnostic markers of angiogenesis in normal or diseased tissues both in vivo and ex vivo.

IPC 8 full level

C07K 7/08 (2006.01); A61K 38/10 (2006.01); A61P 9/10 (2006.01); A61P 35/00 (2006.01); A61P 35/04 (2006.01)

IPC 8 main group level

C07K (2006.01)

CPC (source: EP US)

A61P 9/00 (2018.01 - EP); A61P 9/10 (2018.01 - EP); A61P 35/00 (2018.01 - EP); A61P 35/04 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07K 7/08 (2013.01 - EP US)

Citation (search report)

  • [A] WO 0040597 A1 20000713 - UNIV SOUTHERN CALIFORNIA [US]
  • [X] GONZALEZ ANNETTE M ET AL: "Complex interactions between the laminin alpha 4 subunit and integrins regulate endothelial cell behavior in vitro and angiogenesis in vivo.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 10 DEC 2002, vol. 99, no. 25, 10 December 2002 (2002-12-10), pages 16075 - 16080, XP002440966, ISSN: 0027-8424
  • [X] KIKKAWA Y ET AL: "Isolation and characterization of laminin-10/11 secreted by human lung carcinoma cells. laminin-10/11 mediates cell adhesion through integrin alpha3 beta1", JOURNAL OF BIOLOGICAL CHEMISTRY (ONLINE), AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY,, US, vol. 273, no. 25, 19 June 1998 (1998-06-19), pages 15854 - 15859, XP002989633, ISSN: 1083-351X
  • [X] KURKINEN M ET AL: "In vitro synthesis of laminin and entactin polypeptides.", THE JOURNAL OF BIOLOGICAL CHEMISTRY 25 MAY 1983, vol. 258, no. 10, 25 May 1983 (1983-05-25), pages 6543 - 6548, XP002440974, ISSN: 0021-9258
  • [T] AKALU ABEBE ET AL: "Inhibition of angiogenesis and tumor metastasis by targeting a matrix immobilized cryptic extracellular matrix epitope in laminin.", CANCER RESEARCH 1 MAY 2007, vol. 67, no. 9, 1 May 2007 (2007-05-01), pages 4353 - 4363, XP002440967, ISSN: 0008-5472

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2004087734 A2 20041014; WO 2004087734 A3 20050728; AT E480552 T1 20100915; AU 2004225986 A1 20041014; AU 2004225986 B2 20101111; CA 2520372 A1 20041014; CA 2520372 C 20131224; DE 602004029016 D1 20101021; EP 1611151 A2 20060104; EP 1611151 A4 20070822; EP 1611151 B1 20100908; JP 2006524241 A 20061026; US 2004224896 A1 20041111; US 2009226369 A1 20090910; US 7387998 B2 20080617

DOCDB simple family (application)

US 2004009332 W 20040326; AT 04758409 T 20040326; AU 2004225986 A 20040326; CA 2520372 A 20040326; DE 602004029016 T 20040326; EP 04758409 A 20040326; JP 2006509356 A 20040326; US 11828808 A 20080512; US 79762604 A 20040309