EP 1615637 A1 20060118 - PHARMACEUTICAL USE OF SUBSTITUTED 1,2,4-TRIAZOLES
Title (en)
PHARMACEUTICAL USE OF SUBSTITUTED 1,2,4-TRIAZOLES
Title (de)
PHARMAZEUTISCHE VERWENDUNG VON SUBSTITUIERTEN 1,2,4-TRIAZOLEN
Title (fr)
UTILISATION PHARMACEUTIQUE DE 1,2,4-TRIAZOLES SUBSTITUEES
Publication
Application
Priority
- DK 2004000249 W 20040406
- DK PA200300566 A 20030411
- US 46736203 P 20030502
Abstract (en)
[origin: WO2004089367A1] The use of substituted 1,2,4-triazoles for modulating the activity of 11 beta-hydroxysteroid dehydrogenase type 1 (11 betaHSD1) and the use of these compounds as pharmaceutical compositions has been described. Also a novel class of substituted 1,2,4-triazoles, their use in therapy, pharmaceutical compositions comprising the compounds, as well as their use in the manufacture of medicaments has been described. The present compounds are modulators and more specifically inhibitors of the activity of 11 betaHSD1 and may be useful in the treatment, prevention and/or prophylaxis of a range of medical disorders where a decreased intracellular concentration of active glucocorticoid is desirable.
IPC 1-7
IPC 8 full level
A61K 31/4196 (2006.01); A61P 3/00 (2006.01); A61P 3/10 (2006.01); C07D 249/12 (2006.01); C07D 401/04 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 403/06 (2006.01); C07D 403/10 (2006.01); C07D 403/14 (2006.01); C07D 405/04 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/04 (2006.01); C07D 409/14 (2006.01); C07D 417/04 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01)
CPC (source: EP)
A61K 31/4196 (2013.01); A61P 3/00 (2017.12); A61P 3/04 (2017.12); A61P 3/06 (2017.12); A61P 3/10 (2017.12); A61P 5/50 (2017.12); A61P 9/00 (2017.12); A61P 9/10 (2017.12); A61P 25/00 (2017.12); A61P 43/00 (2017.12); C07D 249/12 (2013.01); C07D 401/04 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/06 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 409/14 (2013.01); C07D 417/04 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01)
Citation (search report)
See references of WO 2004089367A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004089367 A1 20041021; EP 1615637 A1 20060118; JP 2006522745 A 20061005
DOCDB simple family (application)
DK 2004000249 W 20040406; EP 04725885 A 20040406; JP 2006504352 A 20040406