EP 1615899 A1 20060118 - ALPHA-SUBSTITUTED CARBOXYLIC ACIDS AS PPAR MODULATORS
Title (en)
ALPHA-SUBSTITUTED CARBOXYLIC ACIDS AS PPAR MODULATORS
Title (de)
ALPHA-SUBSTITUIERTE CARBONSÄUREN ALS PPAR MODULATOREN
Title (fr)
ACIDES CARBOXYLIQUES ALPHA-SUBSTITUES COMME MODULATEURS DU RECEPTEUR ACTIVE PAR LES PROLIFERATEURS DE PEROXYSOME (PPAR)
Publication
Application
Priority
- IB 2004001159 W 20040401
- US 46321303 P 20030415
Abstract (en)
[origin: WO2004092145A1] Alpha substituted carboxylic acids of formula (I): wherein R' and R2 are as defined in the specification and R3 is A) formula (II); B) formula (III); C) formula (IV); and D) formula (V); wherein Y, Art, Are, AP, R4, R5, R6, R7, R6, R9, R9a, R10, R", R12, R17, ring A, and p are as defined in the specification; pharmaceutical compositions containing effective amounts of said compounds or their salts are useful for treating PPAR, specifically PPAR alpha/y related disorders, such as diabetes, dyslipidemia, obesity and inflammatory disorders.
IPC 1-7
C07D 263/32; C07D 213/66; C07D 405/06; C07C 59/125; C07C 61/04; C07D 413/12; C07D 401/04; C07D 307/79; C07D 411/12; C07D 413/14; C07D 249/06; C07D 417/14
IPC 8 full level
C07C 59/125 (2006.01); C07C 59/68 (2006.01); C07C 61/04 (2006.01); C07C 62/34 (2006.01); C07C 249/06 (2006.01); C07C 271/14 (2006.01); C07C 271/16 (2006.01); C07C 311/08 (2006.01); C07C 311/29 (2006.01); C07C 317/22 (2006.01); C07D 213/66 (2006.01); C07D 249/06 (2006.01); C07D 263/32 (2006.01); C07D 307/79 (2006.01); C07D 401/04 (2006.01); C07D 405/06 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/14 (2006.01)
CPC (source: EP KR)
A61P 3/00 (2017.12 - EP); A61P 3/04 (2017.12 - EP); A61P 3/06 (2017.12 - EP); A61P 3/08 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 7/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07C 59/68 (2013.01 - EP); C07C 62/34 (2013.01 - EP); C07C 271/14 (2013.01 - EP); C07C 271/16 (2013.01 - EP); C07C 311/08 (2013.01 - EP); C07C 311/29 (2013.01 - EP); C07C 317/22 (2013.01 - EP); C07D 213/66 (2013.01 - EP); C07D 249/06 (2013.01 - EP); C07D 263/32 (2013.01 - EP KR); C07D 307/79 (2013.01 - EP KR); C07D 401/04 (2013.01 - EP KR); C07D 405/06 (2013.01 - EP); C07D 413/12 (2013.01 - EP); C07D 413/14 (2013.01 - EP); C07D 417/14 (2013.01 - EP); C07C 2601/04 (2017.04 - EP)
Citation (search report)
See references of WO 2004092145A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004092145 A1 20041028; WO 2004092145 A8 20050512; AP 2005003418 A0 20051231; AR 044514 A1 20050914; AU 2004230316 A1 20041028; BR PI0409429 A 20060418; CA 2521915 A1 20041028; CL 2004000800 A1 20050304; CN 1805943 A 20060719; EA 200501462 A1 20060428; EC SP056105 A 20060301; EP 1615899 A1 20060118; IS 8033 A 20050915; JP 2006523671 A 20061019; KR 20060009846 A 20060201; MA 27764 A1 20060201; MX PA05010967 A 20051128; NL 1025946 A1 20041018; NL 1025946 C2 20050201; NO 20055370 D0 20051114; NO 20055370 L 20060112; OA 13157 A 20061213; PA 8600201 A1 20050204; PE 20050415 A1 20050613; TN SN05262 A1 20070710; TW 200510353 A 20050316; UY 28266 A1 20041130; ZA 200508362 B 20061129
DOCDB simple family (application)
IB 2004001159 W 20040401; AP 2005003418 A 20040401; AR P040101236 A 20040413; AU 2004230316 A 20040401; BR PI0409429 A 20040401; CA 2521915 A 20040401; CL 2004000800 A 20040414; CN 200480016736 A 20040401; EA 200501462 A 20040401; EC SP056105 A 20051014; EP 04725121 A 20040401; IS 8033 A 20050915; JP 2006506478 A 20040401; KR 20057019591 A 20051014; MA 28552 A 20051014; MX PA05010967 A 20040401; NL 1025946 A 20040414; NO 20055370 A 20051114; OA 1200500283 A 20040401; PA 8600201 A 20040414; PE 2004000361 A 20040412; TN SN05262 A 20051014; TW 93110410 A 20040414; UY 28266 A 20040413; ZA 200508362 A 20051014