Title (en)

PHARMACEUTICAL COMPOSITION CONTAINING RIBAVIRIN AS ACTIVE SUBSTANCE AND METHOD OF MANUFACTURING THEREOF

Title (de)

RIBAVIRIN ENTHALTENDE PHARMAZEUTISCHE ZUSAMMENSETZUNG UND EIN VERFAHREN ZUR HERSTELLUNG DES AKTIVEN BESTANDTEILS

Title (fr)

PREPARATION PHARMACEUTIQUE DONT LE PRINCIPE ACTIF EST LA RIBAVINE, ET SON PROCEDE DE FABRICATION

Publication

EP 1617824 A1 20060125 (EN)

Application

EP 04729818 A 20040428

Priority

• CZ 2004000023 W 20040428
• CZ 20031202 A 20030429

Abstract (en)

[origin: WO2004096187A1] The invention relates to a pharmaceutical composition which is a freely flowing granulate prepared using the wet granulation of a mixture, wetted with water, of ribavirin, at least one pharmaceutically acceptable filler selected from the group including cellulose and its derivatives and carbonates, phosphates, sulfates and silicates of metals, and optionally at least one pharmaceutically acceptable excipient, and also a method of the manufacture thereof. The pharmaceutical composition according to the invention ensures the perfect stability of the composition, even in case of a high ratio of the active substance in it, and the immediately release of the active substance from a dosage form, when administered orally in the form of capsules or tablets.

IPC 1-7

A61K 9/48; A61P 31/12; A61K 31/7056

IPC 8 full level

A61K 9/16 (2006.01); A61K 9/48 (2006.01); A61K 31/7056 (2006.01); A61P 31/12 (2006.01)

CPC (source: EP)

A61K 9/1652 (2013.01); A61K 31/7056 (2013.01); A61P 31/12 (2017.12)

Citation (search report)

See references of WO 2004096187A1

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2004096187 A1 20041111; CZ 20031202 A3 20050112; CZ 298224 B6 20070725; EP 1617824 A1 20060125

DOCDB simple family (application)

CZ 2004000023 W 20040428; CZ 20031202 A 20030429; EP 04729818 A 20040428