EP 1620441 A1 20060201 - THIADIAZINE DERIVATIVES AND USE THEREOF AS POSITIVE AMPA RECEPTOR MODULATORS
Title (en)
THIADIAZINE DERIVATIVES AND USE THEREOF AS POSITIVE AMPA RECEPTOR MODULATORS
Title (de)
THIADIAZINDERIVATE UND DEREN VERWENDUNG ALS POSITIVE AMPA-REZEPTORMODULATOREN
Title (fr)
DERIVES DE THIADIAZINE ET LEUR UTILISATION COMME MODULATEURS POSITIFS DES RECEPTEURS AMPA
Publication
Application
Priority
- FR 2004001070 W 20040504
- FR 0305448 A 20030505
Abstract (en)
[origin: WO2004099217A1] The invention relates to thiadiazine derivatives and to the use thereof as positive AMPA receptor modulators. More specifically, the invention relates to compounds having formula (I), wherein: A represents a thienyl, furyl, pyrrolyl, oxathiole, thiazole, isothiazole, oxazole or imidazole group; -. ç represents a single bond or a double bond; R1 represents a hydrogen atom, a linear or branched (C1-C6) alkyl group which is optionally substituted by one or more halogen atoms, or a (C1-C6) alkoxy (C1-C6) alkyl group; R2 represents a hydrogen atom or a linear or branched (C1-C6) alkyl group which is optionally substituted by one or more halogen atoms; and R3 represents a hydrogen atom or a group which is selected from linear or branched (C1-C6) alkyl, CONHR' or SO2NHR', in which R' represents a linear or branched (C1-C6) alkyl group. The invention also relates to the enantiomers and diastereoisomers of the above-mentioned compounds as well as to the pharmaceutically-acceptable base or acid addition salts thereof. The invention further relates to the use of same as medicaments.
IPC 1-7
IPC 8 full level
A61P 25/18 (2006.01); C07D 513/04 (2006.01)
CPC (source: EP KR US)
A61P 25/14 (2017.12 - EP); A61P 25/18 (2017.12 - EP); A61P 25/22 (2017.12 - EP); A61P 25/24 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 513/04 (2013.01 - EP KR US)
Citation (search report)
See references of WO 2004099217A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
Designated extension state (EPC)
AL HR LT LV MK
DOCDB simple family (publication)
FR 2854634 A1 20041112; FR 2854634 B1 20050708; AR 044245 A1 20050907; AU 2004236005 A1 20041118; AU 2004236005 B2 20100121; BR PI0410002 A 20060425; CA 2524377 A1 20041118; CA 2524377 C 20100824; CN 100363368 C 20080123; CN 1798750 A 20060705; EA 009240 B1 20071228; EA 200501696 A1 20060630; EP 1620441 A1 20060201; GE P20084318 B 20080310; HK 1088327 A1 20061103; JP 2006525292 A 20061109; JP 4461139 B2 20100512; KR 100741235 B1 20070719; KR 20060006830 A 20060119; MA 27732 A1 20060102; MX PA05011823 A 20060525; MY 136694 A 20081128; NO 20055695 L 20051201; NZ 543214 A 20090228; UA 80046 C2 20070810; US 2007004709 A1 20070104; US 7476668 B2 20090113; WO 2004099217 A1 20041118; ZA 200508660 B 20070131
DOCDB simple family (application)
FR 0305448 A 20030505; AR P040101515 A 20040504; AU 2004236005 A 20040504; BR PI0410002 A 20040504; CA 2524377 A 20040504; CN 200480014886 A 20040504; EA 200501696 A 20040504; EP 04742632 A 20040504; FR 2004001070 W 20040504; GE AP2004009092 A 20040504; HK 06108870 A 20060810; JP 2006505830 A 20040504; KR 20057020817 A 20051102; MA 28567 A 20051021; MX PA05011823 A 20040504; MY PI20041647 A 20040430; NO 20055695 A 20051201; NZ 54321404 A 20040504; UA A200511454 A 20040504; US 55574305 A 20051104; ZA 200508660 A 20040504