EP 1622872 A1 20060208 - 1,2,4-SUBSTITUERTE 1,2,3,4-TETRAHYDRO-AND 1,2 DIHYDRO-QUINOLINE AND 1,2,3,4-TETRAHYDRO-QUINOXALINE DERIVATIVES AS CETP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROSIS AND OBESITY
Title (en)
1,2,4-SUBSTITUERTE 1,2,3,4-TETRAHYDRO-AND 1,2 DIHYDRO-QUINOLINE AND 1,2,3,4-TETRAHYDRO-QUINOXALINE DERIVATIVES AS CETP INHIBITORS FOR THE TREATMENT OF ATHEROSCLEROSIS AND OBESITY
Title (de)
1,2,4-SUBSTITUIERTE 1,2,3,4-TETRAHYDRO- UND 1,2 DIHYDRO-CHINOLIN UND 1,2,3,4-TETRAHYDROCHINOXALINDERIVATE ALS CETP-INHIBITOREN ZUR BEHANDLUNG VON ATHEROSKLEROSE UND OBESITAS
Title (fr)
DERIVES DE 1,2,3,4-TETRAHYDRO- ET 1,2 DIHYDRO-QUINOLEINE ET 1,2,3,4-TETRAHYDRO-QUINOXALINE 1,2,4-SUBSTITUES, UTILES COMME INHIBITEURS DE CETP POUR LE TRAITEMENT DE L'ATHEROSCLEROSE ET DE L'OBESITE
Publication
Application
Priority
- IB 2004000836 W 20040315
- US 45827403 P 20030328
Abstract (en)
[origin: WO2004085401A1] Quinoline and quinoxaline compounds of formula I and III wherein the subtituent are as defined in claims 1 and 15, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans.
IPC 1-7
C07D 215/14; C07D 215/50; C07D 215/12; C07D 241/42; C07D 401/04; C07D 401/12; C07D 409/12; C07D 405/12; C07D 413/12; C07D 417/12; C07D 403/06; C07D 401/06; C07D 413/06; C07D 405/06; C07D 417/06
IPC 8 full level
C07D 215/12 (2006.01); C07D 215/14 (2006.01); C07D 241/42 (2006.01); C07D 401/04 (2006.01); C07D 401/06 (2006.01); C07D 401/12 (2006.01); C07D 403/06 (2006.01); C07D 403/10 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 409/06 (2006.01); C07D 409/12 (2006.01); C07D 413/06 (2006.01); C07D 413/10 (2006.01); C07D 413/12 (2006.01); C07D 417/06 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01)
CPC (source: EP KR)
A61K 31/47 (2013.01 - KR); A61P 3/00 (2017.12 - EP); A61P 3/04 (2017.12 - EP); A61P 3/06 (2017.12 - EP); A61P 3/10 (2017.12 - EP); A61P 9/00 (2017.12 - EP); A61P 9/10 (2017.12 - EP); A61P 9/12 (2017.12 - EP); A61P 15/10 (2017.12 - EP); A61P 25/00 (2017.12 - EP); A61P 25/28 (2017.12 - EP); A61P 29/00 (2017.12 - EP); A61P 31/04 (2017.12 - EP); A61P 39/06 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 215/12 (2013.01 - EP KR); C07D 215/14 (2013.01 - EP KR); C07D 215/50 (2013.01 - KR); C07D 241/42 (2013.01 - EP KR); C07D 401/04 (2013.01 - EP KR); C07D 401/06 (2013.01 - EP KR); C07D 401/12 (2013.01 - EP KR); C07D 403/06 (2013.01 - EP KR); C07D 403/10 (2013.01 - EP KR); C07D 405/06 (2013.01 - EP KR); C07D 405/12 (2013.01 - EP); C07D 409/06 (2013.01 - EP); C07D 409/12 (2013.01 - EP); C07D 413/06 (2013.01 - EP); C07D 413/10 (2013.01 - EP); C07D 413/12 (2013.01 - EP); C07D 417/06 (2013.01 - EP); C07D 417/12 (2013.01 - EP); C07D 417/14 (2013.01 - EP); C07D 471/04 (2013.01 - EP); C07D 495/04 (2013.01 - EP)
Citation (search report)
See references of WO 2004085401A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004085401 A1 20041007; WO 2004085401 A8 20051201; AR 044507 A1 20050914; AU 2004224082 A1 20041007; BR PI0408897 A 20060418; CA 2520405 A1 20041007; CL 2004000639 A1 20050204; CN 1795177 A 20060628; EA 200501376 A1 20060428; EC SP056040 A 20060127; EP 1622872 A1 20060208; GT 200400050 A 20050302; HR P20050859 A2 20060228; JP 2006521344 A 20060921; KR 100729883 B1 20070618; KR 20050115938 A 20051208; MA 27828 A1 20060403; MX PA05010456 A 20060321; NL 1025839 A1 20040930; NL 1025839 C2 20060906; NO 20054989 D0 20051026; NO 20054989 L 20051216; OA 13153 A 20061213; PA 8598901 A1 20041126; PE 20050389 A1 20050530; TN SN05243 A1 20070611; TW 200508222 A 20050301; TW I285641 B 20070821; UY 28243 A1 20041108; ZA 200507819 B 20070425
DOCDB simple family (application)
IB 2004000836 W 20040315; AR P040101024 A 20040326; AU 2004224082 A 20040315; BR PI0408897 A 20040315; CA 2520405 A 20040315; CL 2004000639 A 20040325; CN 200480014645 A 20040315; EA 200501376 A 20040315; EC SP056040 A 20050926; EP 04720668 A 20040315; GT 200400050 A 20040323; HR P20050859 A 20050928; JP 2006506369 A 20040315; KR 20057018383 A 20050928; MA 28519 A 20050928; MX PA05010456 A 20040315; NL 1025839 A 20040326; NO 20054989 A 20051026; OA 1200500269 A 20040315; PA 8598901 A 20040326; PE 2004000323 A 20040326; TN SN05243 A 20050928; TW 93108314 A 20040326; UY 28243 A 20040325; ZA 200507819 A 20050927