EP 1625138 A4 20100623 - PROTECTED MONOMERS
Title (en)
PROTECTED MONOMERS
Title (de)
GESCHÜTZTE MONOMERE
Title (fr)
MONOMERES PROTEGES
Publication
Application
Priority
- US 2004011822 W 20040416
- US 46377203 P 20030417
- US 46580203 P 20030425
- US 46566503 P 20030425
- US 46961203 P 20030509
- US 49398603 P 20030808
- US 49459703 P 20030811
- US 50634103 P 20030926
- US 51024603 P 20031009
- US 51031803 P 20031010
- US 51845303 P 20031107
- US 2004007070 W 20040308
- US 2004010586 W 20040405
- US 2004011255 W 20040409
Abstract (en)
[origin: WO2004094345A2] This invention relates to protected monomers for the synthesis of iRNA agents.
IPC 8 full level
C07C 233/00 (2006.01); C07D 207/00 (2006.01); C07H 7/04 (2006.01); C07H 7/06 (2006.01); C07H 19/00 (2006.01); C07H 19/02 (2006.01); C07H 19/04 (2006.01); C07H 19/044 (2006.01); C07H 19/052 (2006.01); C07H 19/056 (2006.01); C07H 19/067 (2006.01); C07H 19/14 (2006.01); C07H 19/167 (2006.01); C07H 19/22 (2006.01); C07H 19/23 (2006.01); C07H 19/24 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C07H 23/00 (2006.01); C12N 15/00 (2006.01); C12N 15/11 (2006.01)
IPC 8 main group level
C07C (2006.01)
CPC (source: EP)
A61K 31/00 (2013.01); A61P 1/04 (2017.12); A61P 1/16 (2017.12); A61P 7/02 (2017.12); A61P 9/08 (2017.12); A61P 9/10 (2017.12); A61P 11/00 (2017.12); A61P 11/06 (2017.12); A61P 13/08 (2017.12); A61P 17/02 (2017.12); A61P 19/02 (2017.12); A61P 25/00 (2017.12); A61P 25/02 (2017.12); A61P 25/14 (2017.12); A61P 25/16 (2017.12); A61P 25/28 (2017.12); A61P 29/00 (2017.12); A61P 31/12 (2017.12); A61P 31/16 (2017.12); A61P 31/18 (2017.12); A61P 31/22 (2017.12); A61P 33/00 (2017.12); A61P 33/06 (2017.12); A61P 35/00 (2017.12); A61P 35/02 (2017.12); A61P 37/06 (2017.12); A61P 43/00 (2017.12); C07H 7/04 (2013.01); C07H 7/06 (2013.01); C07H 19/02 (2013.01); C07H 19/04 (2013.01); C07H 19/044 (2013.01); C07H 19/052 (2013.01); C07H 19/056 (2013.01); C07H 19/067 (2013.01); C07H 19/14 (2013.01); C07H 19/167 (2013.01); C07H 19/22 (2013.01); C07H 19/23 (2013.01); C07H 19/24 (2013.01); C07H 21/02 (2013.01); C07H 23/00 (2013.01)
Citation (search report)
- [I] WO 9641809 A1 19961227 - UNIV COLORADO [US]
- [XI] SCARINGE, STEPHEN A.: "Advanced 5'-silyl-2'-orthoester approach to RNA oligonucleotide synthesis", METHODS IN ENZYMOLOGY ( 2000 ), 317 (RNA-LIGAND INTERACTIONS, PT. A), vol. 317, 2000, pages 3 - 18, XP009133517, ISSN: 0076-6879
- [XI] BALKRISHEN BHAT ET AL.: "Deoxyadenosine and Thymidine Bases Held Proximal and Distal by Means of a Covalently-Linked Dimensional Analogue of dA·dT: Intramolecular vs Intermolecular Hydrogen Bonding", J. AM. CHEM. SOC., vol. 118, no. 44, 6 November 1996 (1996-11-06), pages 10744 - 10751, XP002582187, DOI: 10.1021/ja9618255
- [X] TONGQIAN CHEN ET AL.: "Synthesis and Deprotection of Oligonucleotides under Aprotic Conditions", ORG. LETT., vol. 2, no. 23, 27 October 2000 (2000-10-27), pages 3691 - 3694, XP002581833, DOI: 10.1021/ol006604p
- [I] HELEN M. -P. ET AL.: "Synthesis of a 3-methyluridine phosphoramidite to investigate the role of methylation in a ribosomal RNA hairpin", BIOORGANIC & MEDICINAL CHEMISTRY, vol. 10, no. 2, 27 August 2001 (2001-08-27), pages 325 - 332, XP002581834, DOI: 10.1016/S0968-0896(01)00283-8
- [X] GROTLI M ET AL: "Solid-phase Synthesis of Branched RNA and Branched DNA/RNA Chimeras", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL LNKD- DOI:10.1016/S0040-4020(97)00731-X, vol. 53, no. 33, 18 August 1997 (1997-08-18), pages 11317 - 11346, XP004106005, ISSN: 0040-4020
- [X] GAFFNEY B L ET AL: "The influence of the purine 2-amino group on DNA conformation and stability-II", TETRAHEDRON, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL LNKD- DOI:10.1016/0040-4020(84)85098-X, vol. 40, no. 1, 1 January 1984 (1984-01-01), pages 3 - 13, XP026629595, ISSN: 0040-4020, [retrieved on 19840101]
- See references of WO 2004094345A2
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004094345 A2 20041104; WO 2004094345 A3 20051110; WO 2004094345 A8 20160630; AU 2004232964 A1 20041104; AU 2004232964 B2 20110922; CA 2522349 A1 20041104; EP 1625138 A2 20060215; EP 1625138 A4 20100623; JP 2007525453 A 20070906; JP 4991288 B2 20120801
DOCDB simple family (application)
US 2004011822 W 20040416; AU 2004232964 A 20040416; CA 2522349 A 20040416; EP 04759940 A 20040416; JP 2006513075 A 20040416