EP 1635814 A1 20060322 - STABLE COMPOSITIONS OF ATORVASTATIN PREPARED WITH WET GRANULATION
Title (en)
STABLE COMPOSITIONS OF ATORVASTATIN PREPARED WITH WET GRANULATION
Title (de)
STABILE, MITTELS NASSGRANULIERUNG HERGESTELLTE ATORVASTATIN ZUSAMMENSETZUNGEN
Title (fr)
COMPOSITIONS STABLES D'ATORVASTATINE PREPAREES PAR GRANULATION PAR VOIE HUMIDE
Publication
Application
Priority
- IB 2004001862 W 20040601
- US 47811903 P 20030612
Abstract (en)
[origin: WO2004110431A1] A wet granulated pharmaceutical composition comprising atorvastatin or a pharmaceutically acceptable salt thereof with less than about 5 weight% of an alkaline earth metal salt additive with a disintegrant which provides the atorvastatin with not more than about 3% atorvastatin lactone based on the ratio of lactone peak area compared to the total drug-related peak integrated areas, as well as said wet granulated pharmaceutical composition comprising atorvastatin or a pharmaceutically acceptable salt thereof in combination with at least one other active drug, methods for preparing said compositions, kits for containing such compositions, and a method of treating hypercholesterolemia and/or hyperlipidemia, osteoporosis, benign prostatic hyperplasia (BPH), and Alzheimer's disease using a therapeutically effective amount of the pharmaceutical compositions.
IPC 1-7
IPC 8 full level
A61K 9/16 (2006.01); A61K 31/40 (2006.01)
CPC (source: EP KR)
A61K 9/16 (2013.01 - KR); A61K 9/1623 (2013.01 - EP); A61K 9/1652 (2013.01 - EP); A61K 31/40 (2013.01 - EP KR); A61P 3/06 (2017.12 - EP); A61P 13/08 (2017.12 - EP); A61P 19/10 (2017.12 - EP); A61P 25/28 (2017.12 - EP)
Citation (search report)
See references of WO 2004110431A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004110431 A1 20041223; AR 044774 A1 20051005; AU 2004246868 A1 20041223; AU 2004246868 B2 20080117; BR PI0411344 A 20060711; CA 2465565 A1 20041212; CN 100434069 C 20081119; CN 1805741 A 20060719; CO 5650230 A2 20060630; EP 1635814 A1 20060322; JP 2006527260 A 20061130; KR 100814218 B1 20080317; KR 20060020666 A 20060306; MX PA05013281 A 20060309; NO 20060022 L 20060103; NZ 543337 A 20080328; RU 2005136745 A 20060727; RU 2332211 C2 20080827; TW 200503690 A 20050201
DOCDB simple family (application)
IB 2004001862 W 20040601; AR P040102008 A 20040610; AU 2004246868 A 20040601; BR PI0411344 A 20040601; CA 2465565 A 20040429; CN 200480016391 A 20040601; CO 05124741 A 20051209; EP 04735614 A 20040601; JP 2006516512 A 20040601; KR 20057023669 A 20051209; MX PA05013281 A 20040601; NO 20060022 A 20060103; NZ 54333704 A 20040601; RU 2005136745 A 20040601; TW 93116894 A 20040611