Global Patent Index - EP 1636199 A2

EP 1636199 A2 20060322 - METHOD FOR THE PRODUCTION OF PHENYLACETIC ACID DERIVATIVES

Title (en)

METHOD FOR THE PRODUCTION OF PHENYLACETIC ACID DERIVATIVES

Title (de)

VERFAHREN ZUR HERSTELLUNG VON PHENYLESSIG DERIVATEN

Title (fr)

PROCEDE DE PRODUCTION DE DERIVES D'ACIDE PHENYLACETIQUE

Publication

EP 1636199 A2 20060322 (DE)

Application

EP 04732562 A 20040513

Priority

  • CH 2004000292 W 20040513
  • CH 8472003 A 20030514

Abstract (en)

[origin: WO2004101540A2] Disclosed is a method for producing (S) (+) phenylacetic acid derivatives of general formula (I), wherein R1 represents a linear or branched alkyl radical with 1 to 6 carbon atoms or optionally substituted benzyl while R2 represents methyl, ethyl, or propyl. The inventive method is characterized in that a compound of general formula (II), wherein R1 has the meaning indicated above and R3 represents a nucleofuge, or a suitable salt of a compound of general formula (II) is reacted with a compound of general formula (III), wherein R2 has the meaning indicated above and R4 represents hydrogen or a hydrolytically cleavable nucleofuge, whereupon the optionally provided protective group R4 is eliminated.

IPC 1-7

C07D 295/12; A61K 31/4453

IPC 8 full level

C07D 295/135 (2006.01)

CPC (source: EP US)

C07D 295/135 (2013.01 - EP US); Y02P 20/55 (2015.11 - EP US)

Citation (search report)

See references of WO 2004101540A2

Designated contracting state (EPC)

AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DOCDB simple family (publication)

WO 2004101540 A2 20041125; WO 2004101540 A3 20050303; EP 1636199 A2 20060322; US 2007123564 A1 20070531; US 7915421 B2 20110329

DOCDB simple family (application)

CH 2004000292 W 20040513; EP 04732562 A 20040513; US 55626804 A 20040513