EP 1636591 A1 20060322 - DETECTION OF PROTEASE-RESISTANT PRION PROTEIN ACCORDING TO AN ASYMMETRIC SPONTANEOUS INTERACTION
Title (en)
DETECTION OF PROTEASE-RESISTANT PRION PROTEIN ACCORDING TO AN ASYMMETRIC SPONTANEOUS INTERACTION
Title (de)
NACHWEIS VON PROTEASE-RESISTENTEM PRION-PROTEIN NACH ASYMMETRISCHER SPONTANER INTERAKTION
Title (fr)
DETECTION D'UNE PROTEINE PRIONIQUE RESISTANT AUX PROTEASES APRES INTERACTION SPONTANEE ASYMETRIQUE
Publication
Application
Priority
- EP 2004006860 W 20040624
- DE 10328830 A 20030626
Abstract (en)
[origin: WO2004113925A1] The invention relates to a method for detecting an infectious prion protein exhibiting an improved sensitivity. For this purpose, a heterologue non-pathogenic protease-sensitive prio protein is added to an examined sample. When the infectious prion protein PrPSc is present in said sample, the prion protein is transformed into protease-resistant prion aggregates by an asymmetric spontaneous interaction.
IPC 1-7
IPC 8 full level
G01N 33/68 (2006.01)
CPC (source: EP US)
G01N 33/6896 (2013.01 - EP US); G01N 2800/2828 (2013.01 - EP US)
Citation (search report)
See references of WO 2004113925A1
Designated contracting state (EPC)
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR
DOCDB simple family (publication)
WO 2004113925 A1 20041229; CA 2524030 A1 20041229; DE 10328830 A1 20050120; EP 1636591 A1 20060322; JP 2009513927 A 20090402; US 2006154239 A1 20060713
DOCDB simple family (application)
EP 2004006860 W 20040624; CA 2524030 A 20040624; DE 10328830 A 20030626; EP 04740273 A 20040624; JP 2006516051 A 20040624; US 30390205 A 20051216